Results 201 to 210 of about 77,694 (290)

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

Cancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li, Jianyuan Zhou, Shuang Wang, Qian Yang, Shulun Nie, Chunwang Ji, Xue Zhang, Shuhan Li, Xuanyu Zhou, Jiahui Chu, Xuehui Wu, Jianqiao Jiao, Ruitao Xu, Qian Xu, Miao Huang, Qiushi Wang, Liliang Dou, Qinqin Hu, Fan Jiang, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Lian Liu   +23 more
wiley   +1 more source

Piper auritum (Kunth) Fungal Endophytes: A Source of Metabolites to Inhibit the Formation of Advanced Glycation End Products

Chemistry &Biodiversity, EarlyView.
Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández, José Antonio Guerrero‐Analco, Juan Luis Monribot‐Villanueva, Luis Bernardo Flores‐Cotera   +3 more
wiley   +1 more source

Karyological analysis of <i>Acanthocephalusranae</i> (Echinorhynchida): expanding the cytogenetic knowledge in acanthocephalans. [PDF]

Zookeys
Orosová M, Marková A.
europepmc   +1 more source

18S Ribosomal RNA [PDF]

, 2020
openaire   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

18S rRNA gene metabarcoding for investigation of gastrointestinal parasite diversity in great cormorants. [PDF]

Sci Rep
Lee S, Alkathiri B, Lee CH, Lee HW, Jeong DH, Kim JY, Choe S, Lee SH.   +7 more
europepmc   +1 more source

Poly(ethylene Glycol)‐Based Peptidomimetics (Pegtides) of Antimicrobial Peptides

ChemBioChem, EarlyView.
Polyethylene glycol (PEG) is commonly used to improve the pharmacokinetics and pharmacodynamics of therapeutic candidates by conjugation. Here PEG is exploited for peptidomimetic conversion of antimicrobial peptides (AMPs), as candidate antibacterial agents, by replacing their polyamide backbone. The pegtides obtained thereby can be readily synthesized
Conor Shine, John R. F. B. Connolly, Robert D. Murphy, Hazel Lafferty, Abdalmalek Alfnikh, Ned P. Buijs, Hawraa Shahrour, Nathaniel I. Martin, Eoghan O'Neill, George Amarandei, Jimmy Muldoon, Marc Maresca, Deirdre Fitzgerald‐Hughes, Marc Devocelle   +13 more
wiley   +1 more source

Reference genes validation in tear fluid for RNA analysis in ocular surface disease. [PDF]

Sci Rep
Ojeda DA, Ahmadzadeh H, Orgul S, Bedoya AG, Gupta S, Held K, Swaminathan SS, Sabater AL.   +7 more
europepmc   +1 more source

Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant

ChemBioChem, Accepted Article.
Gramicidin S (GS) is a cyclic decapeptide derived from two pentapeptides. The C‐terminal thioesterase (TE) domain of gramicidin S synthetase B (GrsB) dimerizes precursor pentapeptides and cyclizes the resulting linear decapeptide. Recently, a GS variant (GS‐SA), in which a single D‐Phe was replaced by L‐Ser(Allyl), was reported via precursor‐directed ...
Sho Konno, Tomoe Mizuguchi, Atsuko Suzuki, Miyu Tanaka, Fumihiro Ishikawa, Akihiro Taguchi, Atsuhiko Taniguchi, Genzoh Tanabe, Yoshio Hayashi   +8 more
wiley   +1 more source

Selection of <i>Sclerodermus pupariae</i> Reference Genes for Quantitative Real-Time PCR. [PDF]

Insects
Zhou T, Feng H, Zhang J, Tang Y, Dong X, Kang K.   +5 more
europepmc   +1 more source