Evaluating RNA status for RT-PCR in extracts of postmortem human brain tissue
Total RNA was extracted from 105 individual postmortem human brain samples representing a range of postmortem conditions. To improve upon parameters currently used to screen for RNA quality, electropherogram patterns generated by the Agilent Bioanalyzer ...
Christine L. Miller +4 more
doaj +1 more source
Marine nematode taxonomy in the DNA age: the present and future of molecular tools to access their biodiversity [PDF]
Molecular taxonomy is one of the most promising yet challenging fields of biology. Molecular markers such as nuclear and mitochondrial genes are being used in a variety of studies surveying marine nematode taxa.
da Silva, Maria Cristina +7 more
core +2 more sources
Human fibroblast interferon RNA transcripts of different sizes in poly(I).poly(C) induced cells [PDF]
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Content, Jean +3 more
core +2 more sources
Ribosomal Dysfunction Is a Common Pathomechanism in Different Forms of Trichothiodystrophy
Mutations in a broad variety of genes can provoke the severe childhood disorder trichothiodystrophy (TTD) that is classified as a DNA repair disease or a transcription syndrome of RNA polymerase II.
Gaojie Zhu +8 more
doaj +1 more source
Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P +5 more
core +1 more source
Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA. [PDF]
The precursor ribosomal RNA is processed by multiple steps of nucleolytic cleavage to generate mature rRNAs. Utp24 is a PIN domain endonuclease in the early 90S precursor of small ribosomal subunit and is proposed to cleave at sites A1 and A2 of pre-rRNA.
Weidong An, Yifei Du, Keqiong Ye
doaj +1 more source
Monophyly of brachiopods and phoronids: reconciliation of molecular evidence with Linnaean classification (the subphylum Phoroniformea nov.) [PDF]
Molecular phylogenetic analyses of aligned 18S rDNA gene sequences from articulate and inarticulate brachiopods representing all major extant lineages, an enhanced set of phoronids and several unrelated protostome taxa, confirm previous indications that ...
Bernard L. Cohen +4 more
core +2 more sources
Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons.
Andrew M. Smith +4 more
semanticscholar +1 more source
Trypanosome diversity in wildlife species from the Serengeti and Luangwa Valley ecosystems [PDF]
<p>Background: The importance of wildlife as reservoirs of African trypanosomes pathogenic to man and livestock is well recognised. While new species of trypanosomes and their variants have been identified in tsetse populations, our knowledge of ...
Barbara Mable +11 more
core +3 more sources
Cell arrest and cell death in mammalian preimplantation development [PDF]
The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
A Bettegowda +57 more
core +12 more sources

