The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted [PDF]
Frontiers in Microbiology, 2020 Synthesis and assembly of ribosomal components are fundamental cellular processes and generally well-conserved within the main groups of organisms. Yet, provocative variations to the general schemes exist. We have discovered an unusual processing pathway
Ulf Birkedal +4 more
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Sequence specific detection of bacterial 23S ribosomal RNA by TLR13
eLife, 2012 Toll-like receptors (TLRs) detect microbial infections and trigger innate immune responses. Among vertebrate TLRs, the role of TLR13 and its ligand are unknown. Here we show that TLR13 detects the 23S ribosomal RNA of both gram-positive and gram-negative
Xiao-Dong Li, Zhijian J Chen
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Types of 23S Ribosomal RNA Point Mutations and Therapeutic Outcomes for Helicobacter pylori
Gut and Liver, 2021 Background/Aims: Point mutations in the 23S ribosomal RNA gene have been associated with Helicobacter pylori clarithromycin resistance. This study aimed to detect the prevalence of these point mutations and to investigate the role of different point ...
Sang Yoon Kim +7 more
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rRNA loss induced by rifampicin addition in Escherichia coli reflects extraction artifacts rather than in vivo degradation [PDF]
Scientific ReportsWhen measuring RNA stability in Escherichia coli, RNA synthesis is usually stopped using rifampicin. Although rRNAs are considered stable in vivo, Hamouche et al. Ribosomal RNA degradation induced by the bacterial RNA polymerase inhibitor rifampicin. RNA
Mathilde Burck +4 more
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Journal of Infection in Developing Countries, 2016 Introduction: Avian mycoplasmas impose a significant economic burden to the poultry industry. In recent years, macrolide-resistant Mycoplasma gallisepticum have occasionally been encountered in Egypt. Methodology: This study was designed to document the
Ahmed M Ammar +4 more
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Transcriptomic profiling of ceftriaxone-tolerant phenotypes of Neisseria gonorrhoeae reveals downregulation of ribosomal genes — a pilot study [PDF]
Microbiology SpectrumAntibiotic tolerance is associated with failure of antibiotic treatment and accelerates the development of antimicrobial resistance. The molecular mechanisms underlying antimicrobial tolerance remain poorly understood.
Sheeba Santhini Manoharan-Basil +5 more
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Hidden hemoplasma species within the “Candidatus Mycoplasma haemominutum” lineage in Thai cats revealed by analyses of two independent genetic markers [PDF]
Parasites & VectorsBackground Hemotropic Mycoplasma spp. (hemoplasmas) parasitize erythrocytes and cause hemolytic anemia in several mammalian species, including cats.
Kritsada Thongmeesee +10 more
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Structure of Ribosome-Inactivating Protein from Mirabilis jalapa and Its L12-Stalk-Dependent Inhibition of Escherichia coli Ribosome [PDF]
ToxinsMirabilis antiviral protein (MAP) is the type I ribosome-inactivating protein (RIP), which consists of an RNA N-glycosylase domain with no carbohydrate-binding domain.
Nanami Nishida +7 more
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Nucleic Acids Research, 2021 Bacteria have evolved sophisticated mechanisms to deliver potent toxins into bacterial competitors or into eukaryotic cells in order to destroy rivals and gain access to a specific niche or to hijack essential metabolic or signaling pathways in the host.
D. Jurėnas +7 more
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Types of 23S Ribosomal RNA Point Mutations Affecting Eradication Rates in Clarithromycin-Based Triple Therapy [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023 Objectives The A2142G and A2143G mutations in the 23S ribosomal ribonucleic acid (rRNA) of Helicobacter pylori are the most common mutations associated with clarithromycin resistance. This study aimed to determine the differences in H. pylori eradication
Gihong Park +4 more
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