Results 41 to 50 of about 93,732 (342)

Stress tolerance-related genetic traits of fish pathogen Flavobacterium psychrophilum in a mature biofilm [PDF]

, 2018
Indexación: Scopus.Flavobacterium psychrophilum is the causative agent of bacterial cold-water disease and rainbow trout fry syndrome, and hence this bacterium is placed among the most important salmonid pathogens in the freshwater aquaculture industry ...
Avendaño-Herrera, R., Levipan, H.A., Quezada, J.   +2 more
core   +1 more source

Universal and domain-specific sequences in 23S–28S ribosomal RNA identified by computational phylogenetics

RNA: A publication of the RNA Society, 2015
Comparative analysis of ribosomal RNA (rRNA) sequences has elucidated phylogenetic relationships. However, this powerful approach has not been fully exploited to address ribosome function. Here we identify stretches of evolutionarily conserved sequences,
Stephen M. Doris, D. Smith, Julia Beamesderfer, Benjamin J. Raphael, Judith A Nathanson, S. Gerbi   +5 more
semanticscholar   +1 more source

The 70S Escherichia coli ribosome at 23 å resolution: fitting the ribosomal RNA [PDF]

Structure, 1995
The ribosome--essential for protein synthesis in all organisms--has been an evasive target for structural studies. The best available structures for the 70S Escherichia coli ribosome or its 30S and 50S subunits are based on electron microscopical tilt experiments and are limited in resolution to 28-55 A.
Stark, Holger, Mueller, Florian, Orlova, Elena V., Schatz, Michael, Dube, Prakash, Erdemir, Tarik, Zemlin, Friedrich, Brimacombe, Richard, Heel, Marin van   +8 more
openaire   +3 more sources

Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release. [PDF]

, 2018
Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs).
Clementi, Nina, Erlacher, Matthias David, Faserl, Klaus, Gasser, Catherina, Hoernes, Thomas Philipp, Hüttenhofer, Alexander, Joseph, Simpson, Juen, Michael Andreas, Kreutz, Christoph, Lindner, Herbert, Shi, Xinying, Willi, Jessica   +11 more
core   +3 more sources

Differences in 23S ribosomal RNA mutations between wild-type and mutant macrolide-resistant Chlamydia trachomatis isolates.

Experimental and Therapeutic Medicine, 2015
The aim of the present study was to determine the in vitro susceptibility of wild-type and mutant clinical isolates of Chlamydia (C.) trachomatis strains to erythromycin, azithromycin and josamycin, and to identify the resistance-conferring 23S ribosomal
Yong Jiang, Huifang Zhu, Lina Yang, Yuanjun Liu, Shuping Hou, M. Qi, Quanzhong Liu   +6 more
semanticscholar   +1 more source

Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion

BMC Genomics, 2020
RNA sequencing is a powerful approach to quantify the genome-wide distribution of mRNA molecules in a population to gain deeper understanding of cellular functions and phenotypes.
Chatarin Wangsanuwat, Kellie A. Heom, Estella Liu, M. O’Malley, Siddharth S. Dey   +4 more
semanticscholar   +1 more source

Hfq and RNase R Mediate rRNA Processing and Degradation in a Novel RNA Quality Control Process

mBio, 2020
RNA quality control pathways are critical for cell survival. Here, we describe a new surveillance process involved in the degradation of highly structured and stable ribosomal RNAs.
Ricardo F. dos Santos, José M. Andrade, Joana Pissarra, Murray P. Deutscher, Cecília M. Arraiano   +4 more
doaj   +1 more source

Comprehensive analysis of the pre-ribosomal RNA maturation pathway in a methanoarchaeon exposes the conserved circularization and linearization mode in archaea

RNA Biology, 2020
The ribosomal RNA (rRNA) genes are generally organized as an operon and cotranscribed into a polycistronic precursor; therefore, processing and maturation of pre-rRNAs are essential for ribosome biogenesis.
Lei S. Qi, Jie Li, Jia Jia, Lei Yue, Xiuzhu Dong   +4 more
semanticscholar   +1 more source

Modifications in Thermus thermophilus 23 S Ribosomal RNA Are Centered in Regions of RNA-RNA Contact [PDF]

Journal of Biological Chemistry, 2006
Ribosomal RNA from all organisms contains post-transcriptionally modified nucleotides whose function is far from clear. To gain insight into the molecular interactions of modified nucleotides, we investigated the modification status of Thermus thermophilus 5 S and 23 S ribosomal RNA by mass spectrometry and chemical derivatization/primer extension.
Mengel-Jorgensen, J., Jensen, S.S., Rasmussen, A., Poehlsgaard, J., Iversen, J.J.L., Kirpekar, F.   +5 more
openaire   +4 more sources

cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG. [PDF]

, 2001
Identifying genes that are differentially expressed by Mycobacterium bovis BCG after phagocytosis by macrophages will facilitate the understanding of the molecular mechanisms of host cell-intracellular pathogen interactions. To identify such genes a cDNA-
Centre Gunnels Wood, Irene M. Monahan, Joseph A. Mangan, Martin J. Everett, Ming-shi Li, Philip D. Butcher, Simon J. Waddell, Steve L. Martin   +7 more
core   +3 more sources