Results 51 to 60 of about 93,732 (342)

Atomic Mutagenesis of the Ribosome: Towards a Molecular Understanding of Translation

CHIMIA, 2013
The multifaceted repertoire of non-protein-coding RNAs (ncRNAs) in organisms of all three domains of life emphasizes their fundamental role in biology.
Norbert Polacek
doaj   +1 more source

Multiple prebiotic metals mediate translation. [PDF]

, 2018
Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a ...
Bowman, Jessica C, Bray, Marcus S, Glass, Jennifer B, Haynes, Jay William, Hud, Nicholas V, Lenz, Timothy K, Petrov, Anton S, Reddi, Amit R, Williams, Loren Dean   +8 more
core   +1 more source

Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine

Scientific Reports, 2017
Eubacterial ribosomal large-subunit methyltransferase H (RlmH) methylates 23S ribosomal RNA pseudouridine 1915 (Ψ1915), which lies near the ribosomal decoding center.
Cha San Koh, Rohini Madireddy, Timothy J. Beane, Phillip D. Zamore, Andrei A. Korostelev   +4 more
doaj   +1 more source

Comparison of two PCR methods for detection of Leptospira interrogans in formalin-fixed and paraffin-embedded tissues

Memorias do Instituto Oswaldo Cruz, 2012
In this study we compared two polymerase chain reaction (PCR) methods using either 16S ribosomal RNA (rRNA) or 23S rRNA gene primers for the detection of different Leptospira interrogans serovars.
Aleco D'Andrea, Yarelys Zamora Martinez, Rosa Alduina, Vincenzo Monteverde, Carmen Fernandez Molina, Maria Vitale   +5 more
doaj   +1 more source

Sequence coevolution between RNA and protein characterized by mutual information between residue triplets. [PDF]

PLoS ONE, 2012
Coevolving residues in a multiple sequence alignment provide evolutionary clues of biophysical interactions in 3D structure. Despite a rich literature describing amino acid coevolution within or between proteins and nucleic acid coevolution within RNA ...
Relly Brandman, Yigal Brandman, Vijay S Pande   +2 more
doaj   +1 more source

Detection of A2143G, A2142C, and A2142G Point Mutations with Real-Time PCR in Stool Specimens from Children Infected with Helicobacter pylori

Diagnostics, 2022
Reports have indicated an increasing prevalence of clarithromycin resistance in children relative to adults. Thus, it is important to investigate primary clarithromycin resistance before therapy to avoid treatment failure.
Nesrin Gareayaghi, Bekir Kocazeybek
doaj   +1 more source

Comparative pan-genome analysis of Piscirickettsia salmonis reveals genomic divergences within genogroups [PDF]

, 2017
Indexación: Scopus.Piscirickettsia salmonis is the etiological agent of salmonid rickettsial septicemia, a disease that seriously affects the salmonid industry. Despite efforts to genomically characterize P.
Cárcamo, J.G., Espinoza-Rojas, D.A., Figueroa, J.E., Mancilla, M., Maracaja-Coutinho, V., Molina, C.F., Nourdin-Galindo, G., Oliver, C., Ruiz, P., Sánchez, P., Vargas-Chacoff, L., Yañez, A.J.   +11 more
core   +2 more sources

In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation [PDF]

, 2013
Purely in vitro ribosome synthesis could provide a critical step towards unraveling the systems biology of ribosome biogenesis, constructing minimal cells from defined components, and engineering ribosomes with new functions.
Church, George M, Fritz, Brian R, Jewett, Michael C, Timmerman, Laura E   +3 more
core   +2 more sources

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

Nucleic Acids Research, 2013
Helix 69 (H69) is a 19-nt stem-loop region from the large subunit ribosomal RNA. Three pseudouridine (Ψ) modifications clustered in H69 are conserved across phylogeny and known to affect ribosome function. To explore the effects of Ψ on the conformations
Jun Jiang, R. Aduri, C. Chow, J. SantaLucia   +3 more
semanticscholar   +1 more source

The first complete genome sequence of the class Fimbriimonadia in the phylum Armatimonadetes. [PDF]

PLoS ONE, 2014
In this study, we present the complete genome of Fimbriimonas ginsengisoli Gsoil 348T belonging to the class Fimbriimonadia of the phylum Armatimonadetes, formerly called as candidate phylum OP10. The complete genome contains a single circular chromosome
Zi-Ye Hu, Yue-Zhu Wang, Wan-Taek Im, Sheng-Yue Wang, Guo-Ping Zhao, Hua-Jun Zheng, Zhe-Xue Quan   +6 more
doaj   +1 more source