Results 31 to 40 of about 93,732 (342)

Helicobacter pylori Eradication According to Sequencing-Based 23S Ribosomal RNA Point Mutation Associated with Clarithromycin Resistance

Journal of Clinical Medicine, 2019
Background/Aims: Clarithromycin resistance in Helicobacter pylori is associated with point mutations in the 23S ribosomal RNA (rRNA) gene. We investigated the point mutations in the 23S rRNA genes of patients with clarithromycin-resistant H.
S. Seo, B. Do, Jin Gu Kang, H. Kim, M. Jang, Hak-Yang Kim, W. Shin   +6 more
semanticscholar   +1 more source

Purification of 70S Ribosomes from Bacillus subtilis

Bio-Protocol, 2015
The eubacterial ribosome (70S) is a macromolecular complex that is composed of a small (30S) subunit and a large (50S) subunit. The small subunit comprises the 16S ribosomal RNA (rRNA) and more than 20 ribosomal proteins (r-proteins), whereas the large ...
Shota Suzuki, Genki Akanuma, Fujio Kawamura   +2 more
doaj   +1 more source

Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in "Saccharomyces cerevisiae" [PDF]

, 2013
The 25S rRNA of yeast contains several base modifications in the functionally important regions. The enzymes responsible for most of these base modifications remained unknown.
Entian, Karl-Dieter, Kötter, Peter, Sharma, Sunny, Watzinger, Peter   +3 more
core   +1 more source

Endonucleolytic processing plays a critical role in the maturation of ribosomal RNA in Methanococcus maripaludis

RNA Biology, 2023
Ribosomal RNA (rRNA) processing and maturation are fundamentally important for ribosome biogenesis, but the mechanisms in archaea, the third form of life, remains largely elusive.
Lei Qi, Huan Liu, Jian Gao, Kai Deng, Xiaoyan Wang, Xiuzhu Dong, Jie Li   +6 more
doaj   +1 more source

Maturation of 23S ribosomal RNA requires the exoribonuclease RNase T [PDF]

RNA, 1999
Ribosomal RNAs are generally synthesized as long, primary transcripts that must be extensively processed to generate the mature, functional species. In Escherichia coli, it is known that the initial 30S precursor is cleaved during its synthesis by the endonuclease RNase III to generate precursors to the 16S, 23S, and 5S rRNAs.
Z, Li, S, Pandit, M P, Deutscher
openaire   +2 more sources

Dissemination of -mediated linezolid resistance among species isolated from a teaching hospital in Beijing, China

Journal of International Medical Research, 2018
Objective The aim of the present study was to report the dissemination of cfr and fexA genes mediated by linezolid resistance among Staphylococcus species.
Jiyong Jian, Liang Chen, Zeqiang Xie, Man Zhang   +3 more
doaj   +1 more source

Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination.

PLoS ONE, 2016
BackgroundWe previously reported the case of a 64-year-old man with mediastinitis caused by Staphylococcus aureus in which the infecting bacterium acquired linezolid resistance after only 14 days treatment with linezolid.
Shigekazu Iguchi, Tomonori Mizutani, Keiichi Hiramatsu, Ken Kikuchi   +3 more
doaj   +1 more source

Point Deletion or Insertion in CmeR-Box, A2075G Substitution in 23S rRNA, and Presence of erm(B) Are Key Factors of Erythromycin Resistance in Campylobacter jejuni and Campylobacter coli Isolated From Central China

Frontiers in Microbiology, 2020
Campylobacter jejuni and Campylobacter coli are major food-borne pathogens that cause bacterial gastroenteritis in humans, and poultry is considered as their most important reservoir.
Yiluo Cheng, Wenting Zhang, Qin Lu, Guoyuan Wen, Zhongzheng Zhao, Qingping Luo, Huabin Shao, Tengfei Zhang   +7 more
doaj   +1 more source

Structure Prediction of RNA Loops with a Probabilistic Approach. [PDF]

PLoS Computational Biology, 2016
The knowledge of the tertiary structure of RNA loops is important for understanding their functions. In this work we develop an efficient approach named RNApps, specifically designed for predicting the tertiary structure of RNA loops, including hairpin ...
Jun Li, Jian Zhang, Jun Wang, Wenfei Li, Wei Wang   +4 more
doaj   +1 more source

Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates

Canadian Journal of Gastroenterology, 2009
BACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens.
R Slinger, L Yan, F Chan, K Forward, G Cooper-Lesins, L Best, D Haldane, S Veldhuyzen van Zanten   +7 more
doaj   +1 more source