Results 21 to 30 of about 69,537 (283)
Single‐chain ribosome inactivating proteins from plants depurinate Escherichia coli 23S ribosomal RNA [PDF]
FEBS Letters, 1991 The rRNA N‐glycosidase activities of the catalytically active A chains of the heterodimeric ribosome inactivating proteins (RIPs) ricin and abrin, the single‐chain RIPs dianthin 30, dianthin 32, and the leaf and seed forms of pokeweed antiviral protein (PAP) were assayed on E. coli ribosomes. All of the single‐chain RIPs were active on E.
Hartley MR +4 more
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Origin and evolution of the Peptidyl Transferase Center from proto-tRNAs
FEBS Open Bio, 2014 We tested the hypothesis of Tamura (2011) [3] that molecules of tRNA gave origin to ribosomes, particularly to the Peptidyl Transferase Center (PTC) of the 23S ribosomal RNA.
Sávio T. Farias +2 more
doaj +1 more source
Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA. [PDF]
Bioorganic & Medicinal Chemistry, 2013 Helix 69 of Escherichia coli 23S rRNA has important roles in specific steps of translation, such as subunit association, translocation, and ribosome recycling. An M13 phage library was used to identify peptide ligands with affinity for helix 69. One selected sequence, NQVANHQ, was shown through a bead assay to interact with helix 69.
Moninderpal Kaur +4 more
semanticscholar +3 more sources
The 23S Ribosomal RNA Mutation Database (23SMDB) [PDF]
Nucleic Acids Research, 1996 The 23S Ribosomal RNA Mutation Database (23SMDB), provides a list of mutated positions in 23S ribosomal RNA from Escherichia coli and the identity of each alteration. Information provided for each mutation includes: (i) a brief description of the phenotypes(s) associated with each mutation, (ii) whether a mutant phenotype has been detected by in vivo ...
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Solution structure of the A loop of 23S ribosomal RNA [PDF]
Proceedings of the National Academy of Sciences, 2001 The A loop is an essential RNA component of the ribosome peptidyltransferase center that directly interacts with aminoacyl (A)-site tRNA. The A loop is highly conserved and contains a ubiquitous 2′- O -methyl ribose modification at position U2552.
S C, Blanchard, J D, Puglisi
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Mitochondrial DNA. Part B. Resources, 2019 The complete chloroplast genome of Juniperus squamata, a shrubby conifer of ornamental value, is determined in this study. The complete chloroplast genome size is 127,792 bp in length.
Siyu Xie +4 more
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Journal of Clinical Medicine, 2019 Background/Aims: Clarithromycin resistance in Helicobacter pylori is associated with point mutations in the 23S ribosomal RNA (rRNA) gene. We investigated the point mutations in the 23S rRNA genes of patients with clarithromycin-resistant H.
S. Seo +6 more
semanticscholar +1 more source
Purification of 70S Ribosomes from Bacillus subtilis
Bio-Protocol, 2015 The eubacterial ribosome (70S) is a macromolecular complex that is composed of a small (30S) subunit and a large (50S) subunit. The small subunit comprises the 16S ribosomal RNA (rRNA) and more than 20 ribosomal proteins (r-proteins), whereas the large ...
Shota Suzuki +2 more
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RNA Biology, 2023 Ribosomal RNA (rRNA) processing and maturation are fundamentally important for ribosome biogenesis, but the mechanisms in archaea, the third form of life, remains largely elusive.
Lei Qi +6 more
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Maturation of 23S ribosomal RNA requires the exoribonuclease RNase T [PDF]
RNA, 1999 Ribosomal RNAs are generally synthesized as long, primary transcripts that must be extensively processed to generate the mature, functional species. In Escherichia coli, it is known that the initial 30S precursor is cleaved during its synthesis by the endonuclease RNase III to generate precursors to the 16S, 23S, and 5S rRNAs.
Z, Li, S, Pandit, M P, Deutscher
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