Results 41 to 50 of about 69,537 (283)

Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine

Scientific Reports, 2017
Eubacterial ribosomal large-subunit methyltransferase H (RlmH) methylates 23S ribosomal RNA pseudouridine 1915 (Ψ1915), which lies near the ribosomal decoding center.
Cha San Koh, Rohini Madireddy, Timothy J. Beane, Phillip D. Zamore, Andrei A. Korostelev   +4 more
doaj   +1 more source

Atomic Mutagenesis of the Ribosome: Towards a Molecular Understanding of Translation

CHIMIA, 2013
The multifaceted repertoire of non-protein-coding RNAs (ncRNAs) in organisms of all three domains of life emphasizes their fundamental role in biology.
Norbert Polacek
doaj   +1 more source

Detection of A2143G, A2142C, and A2142G Point Mutations with Real-Time PCR in Stool Specimens from Children Infected with Helicobacter pylori

Diagnostics, 2022
Reports have indicated an increasing prevalence of clarithromycin resistance in children relative to adults. Thus, it is important to investigate primary clarithromycin resistance before therapy to avoid treatment failure.
Nesrin Gareayaghi, Bekir Kocazeybek
doaj   +1 more source

Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion

BMC Genomics, 2020
RNA sequencing is a powerful approach to quantify the genome-wide distribution of mRNA molecules in a population to gain deeper understanding of cellular functions and phenotypes.
Chatarin Wangsanuwat, Kellie A. Heom, Estella Liu, M. O’Malley, Siddharth S. Dey   +4 more
semanticscholar   +1 more source

Comparison of two PCR methods for detection of Leptospira interrogans in formalin-fixed and paraffin-embedded tissues

Memorias do Instituto Oswaldo Cruz, 2012
In this study we compared two polymerase chain reaction (PCR) methods using either 16S ribosomal RNA (rRNA) or 23S rRNA gene primers for the detection of different Leptospira interrogans serovars.
Aleco D'Andrea, Yarelys Zamora Martinez, Rosa Alduina, Vincenzo Monteverde, Carmen Fernandez Molina, Maria Vitale   +5 more
doaj   +1 more source

Sequence coevolution between RNA and protein characterized by mutual information between residue triplets. [PDF]

PLoS ONE, 2012
Coevolving residues in a multiple sequence alignment provide evolutionary clues of biophysical interactions in 3D structure. Despite a rich literature describing amino acid coevolution within or between proteins and nucleic acid coevolution within RNA ...
Relly Brandman, Yigal Brandman, Vijay S Pande   +2 more
doaj   +1 more source

Comprehensive analysis of the pre-ribosomal RNA maturation pathway in a methanoarchaeon exposes the conserved circularization and linearization mode in archaea

RNA Biology, 2020
The ribosomal RNA (rRNA) genes are generally organized as an operon and cotranscribed into a polycistronic precursor; therefore, processing and maturation of pre-rRNAs are essential for ribosome biogenesis.
Lei S. Qi, Jie Li, Jia Jia, Lei Yue, Xiuzhu Dong   +4 more
semanticscholar   +1 more source

The first complete genome sequence of the class Fimbriimonadia in the phylum Armatimonadetes. [PDF]

PLoS ONE, 2014
In this study, we present the complete genome of Fimbriimonas ginsengisoli Gsoil 348T belonging to the class Fimbriimonadia of the phylum Armatimonadetes, formerly called as candidate phylum OP10. The complete genome contains a single circular chromosome
Zi-Ye Hu, Yue-Zhu Wang, Wan-Taek Im, Sheng-Yue Wang, Guo-Ping Zhao, Hua-Jun Zheng, Zhe-Xue Quan   +6 more
doaj   +1 more source

Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.

PLoS ONE, 2012
In support of the hypothesis of the endosymbiotic origin of eukaryotes, much evidence has been found to support the idea that some organelles of eukaryotic cells originated from bacterial ancestors.
Qiang Xie, Yanhui Wang, Jinzhong Lin, Yan Qin, Ying Wang, Wenjun Bu   +5 more
doaj   +1 more source

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

Nucleic Acids Research, 2013
Helix 69 (H69) is a 19-nt stem-loop region from the large subunit ribosomal RNA. Three pseudouridine (Ψ) modifications clustered in H69 are conserved across phylogeny and known to affect ribosome function. To explore the effects of Ψ on the conformations
Jun Jiang, R. Aduri, C. Chow, J. SantaLucia   +3 more
semanticscholar   +1 more source