Results 91 to 100 of about 96,298 (249)

Genetic and epigenetic variation in 5S ribosomal RNA genes reveals genome dynamics in Arabidopsis thaliana

Nucleic Acids Research, 2018
Organized in tandem repeat arrays in most eukaryotes and transcribed by RNA polymerase III, expression of 5S rRNA genes is under epigenetic control. To unveil mechanisms of transcriptional regulation, we obtained here in depth sequence information on 5S ...
Lauriane Simon, Fernando A. Rabanal, T. Dubos, Cecilia Oliver, Damien Lauber, Axel Poulet, Alexander Vogt, Ariane Mandlbauer, S. Le Goff, Andreas Sommer, H. Duborjal, C. Tatout, A. Probst   +12 more
semanticscholar   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim, Giheon Ha, Minseok Kim, Minjin Kwak, Han‐Jun Kim, Junmin Lee   +5 more
wiley   +1 more source

Stability and Expression of Selected miRNAs, circRNAs, and rRNAs in Swiss Albino Mice Tissues to Preditc Port-Mortem Interval

Brazilian Journal of Forensic Sciences, Medical Law and Bioethics
In forensics, post-mortem interval (PMI) estimation is essential. Researchers have devised various approaches to accurately determine PMI, consequently, ribonucleic acid (RNA) molecules could be useful PMI estimation tool.
Onyekachi Ogbonnaya Iroanya, Tochukwu Frank Egwuatu, Adedolapo Meshach Adebajo, Solomon Tornnee Aloku, David Chima Uche, Stephania Semiire Folorunso   +5 more
doaj   +1 more source

Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome

, 2017
Removal of internal transcribed spacer 2 (ITS2) from pre-ribosomal RNA is essential to make functional ribosomes. This complicated processing reaction begins with a single endonucleolytic cleavage followed by exonucleolytic trimming at both new cleavage ...
Conti, E., Falk, S., Flemming, D., Fromm, L., Hurt, E., Schuller, J., Thoms, M.   +6 more
core   +2 more sources

Mitochondrial Genome Engineering: The Revolution May Not Be CRISPR-Ized. [PDF]

, 2018
In recent years mitochondrial DNA (mtDNA) has transitioned to greater prominence across diverse areas of biology and medicine. The recognition of mitochondria as a major biochemical hub, contributions of mitochondrial dysfunction to various diseases, and
Gammage, Payam A, Minczuk, Michal, Moraes, Carlos T   +2 more
core   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Chromosomal diversification in ribosomal DNA sites in Ancistrus Kner, 1854 (Loricariidae, Ancistrini) from three hydrographic basins of Mato Grosso, Brazil

Comparative Cytogenetics, 2011
Populations of seven Ancistrus species were analyzed from streams and rivers of three hydrographic Brazilian basins. All populations showed different diploid numbers (2n), fundamental numbers (FNs), and karyotypes.
Sandra Mariotto, Liano Centofante, Marcelo Vicari, Roberto Artoni, Orlando Moreira Filho   +4 more
doaj   +1 more source

Tandemly repeated C-C-C-C-A-A hexanucleotide of Tetrahymena rDNA is present elsewhere in the genome and may be related to the alteration of the somatic genome. [PDF]

, 1981
The ribosomal RNA genes of the Tetrahymena macronucleus exist as extrachromosomal, linear molecules. The termini of these molecules have been shown to contain the tandemly repeated hexanucleotide (C-C-C-C-A-A)n.
Blackburn, E, Gall, J, Yao, MC
core  

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

Advanced Science, Volume 13, Issue 1, 5 January 2026.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong‐Hong Lee   +14 more
wiley   +1 more source

Ribosomal RNA fragmentation into short RNAs (rRFs) is modulated in a sex- and population of origin-specific manner

BMC Biology, 2020
Background The advent of next generation sequencing (NGS) has allowed the discovery of short and long non-coding RNAs (ncRNAs) in an unbiased manner using reverse genetics approaches, enabling the discovery of multiple categories of ncRNAs and ...
Tess Cherlin, Rogan Magee, Y. Jing, Venetia Pliatsika, Phillipe Loher, I. Rigoutsos   +5 more
semanticscholar   +1 more source