Representation, searching and discovery of patterns of bases in complex RNA structures [PDF]
We describe a graph theoretic method designed to perform efficient searches for substructural patterns in nucleic acid structural coordinate databases using a simplified vectorial representation.
Artymiuk, P.J. +3 more
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Long-term evolution of 5S ribosomal DNA seems to be driven by birth-and-death processes and selection in "Ensis" razor shells (Mollusca: Bivalvia) [PDF]
, 2009 [Abstract] A study of nucleotide sequence variation of 5S ribosomal DNA from six Ensis species revealed that several 5S ribosomal DNA variants, based on differences in their nontranscribed spacers (NTS), occur in Ensis genomes.
González-Tizón, Ana M. +2 more
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Patterns and regulation of ribosomal RNA transcription in
BMC Microbiology, 2011 Background Borrelia burgdorferi contains one 16S and two tandem sets of 23S-5S ribosomal (r) RNA genes whose patterns of transcription and regulation are unknown but are likely to be critical for survival and persistence in its hosts. Results RT-PCR of B.
Schwartz Ira +3 more
doaj +1 more source
Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites. [PDF]
, 2011 Our work on targeting redox equilibria of malarial parasites propagating in red blood cells has led to the selection of six 1,4-naphthoquinones, which are active at nanomolar concentrations against the human pathogen Plasmodium falciparum in culture and ...
Bauer, Holger +12 more
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Molecular Genetics & Genomic Medicine, 2019 Background Ribosomal RNA (rRNA) consists of four non‐coding RNAs, the 28S, 5.8S, 18S, and 5S rRNA. Abnormal expression of rRNA has been found in multiple tumors, and the methylation of rDNA promoter may affect rRNA expression as an epigenetic regulatory ...
Shanshan Ha +4 more
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Conservation and loss of ribosomal RNA gene sites in diploid and polyploid
BMC Plant Biology, 2011 Background The genus Fragaria comprises species at ploidy levels ranging from diploid (2n = 2x = 14) to decaploid (2n = 10x = 70). Fluorescence in situ hybridization with 5S and 25S rDNA probes was performed to gather cytogenetic information that ...
Liu Bo, Davis Thomas M
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PLoS Genetics, 2014 During transcription, the nascent RNA can invade the DNA template, forming extended RNA-DNA duplexes (R-loops). Here we employ ChIP-seq in strains expressing or lacking RNase H to map targets of RNase H activity throughout the budding yeast genome.
Aziz El Hage +3 more
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Biotechnology & Biotechnological Equipment, 2017 Extraction of RNA of high quality and integrity is essential for gene expression studies and all downstream RNA-based techniques. The leaves of 16 merit Malaysian rice varieties were used to isolate total RNA using five different methods.
Parisa Azizi +7 more
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Trends in evolution of 5S rRNA of deuterostomes: bases and homogeneous clusters
Genetics and Molecular Biology, 2002 Evolution of metazoan 5S rRNA sequences was analyzed through base composition and types, location and frequency of clustered bases. Characters from sequences of protostomes did not show regular trends as compared with paleontology dating or organism ...
Sandra Maria Rodrigues Subacius +1 more
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Change in Nutritional Status Modulates the Abundance of Critical Pre-initiation Intermediate Complexes During Translation Initiation \u3cem\u3ein Vivo\u3c/em\u3e [PDF]
, 2007 In eukaryotic translation initiation, eIF2∙GTP–Met-tRNAiMet ternary complex (TC) interacts with eIF3–eIF1–eIF5 complex to form the multifactor complex (MFC), while eIF2∙GDP associates with eIF2B for guanine nucleotide exchange.
Anderson, James T. +8 more
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