Results 101 to 110 of about 484,088 (306)

New copolymers as hosts of ribosomal RNA

open access: yesBMC Chemistry, 2019
Functionalized copolymers were synthesized and are proposed as hosts of RNA. The copolymers are based on carboxymethyl cellulose and poly-(ethylene glycol)-OH. These copolymers were functionalized with two amino acids, either lysine or histidine, through
Magali Hernández   +6 more
doaj   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan   +3 more
wiley   +1 more source

In vitro Assessment of RNA Polymerase I Activity

open access: yesBio-Protocol, 2017
In eukaryotic cells transcriptional processes are carried out by three different RNA polymerases: RNA polymerase I which specifically transcribes ribosomal RNA (rRNA), RNA polymerase II which transcribes protein-coding genes to yield messenger RNAs ...
Marzia Govoni
doaj   +1 more source

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae.

open access: yesPLoS Genetics, 2020
The first metastable assembly intermediate of the eukaryotic ribosomal small subunit (SSU) is the SSU Processome, a large complex of RNA and protein factors that is thought to represent an early checkpoint in the assembly pathway.
Joshua J Black   +3 more
doaj   +1 more source

A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]

open access: yes, 2009
The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core   +1 more source

Genomic function during the lampbrush chromosome stage of amphibian oogenesis [PDF]

open access: yes, 1966
Throughout its lengthy developmental history the disposition of the genetic material in the amphibian oocyte nucleus differs from that in other cell types.
Crippa, Marco   +3 more
core   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex   +4 more
wiley   +1 more source

Differential distribution of rna and protein in the ribosomal fractions of escherichia coli [PDF]

open access: yes
Differential distribution of RNA and protein in ribosomal fractions of Escherichia ...
Raacke, I. D.
core   +1 more source

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]

open access: yes, 2011
Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah   +7 more
core   +2 more sources

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

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