Results 231 to 240 of about 484,088 (306)

Structure of the hepatitis C virus IRES bound to the human 80S ribosome: Remodeling of the HCV IRES [PDF]

open access: yes, 2005
Boehringer, D.   +4 more
core  

Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs

open access: yesiMetaOmics, EarlyView.
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang   +9 more
wiley   +1 more source

Spatio‐temporal characteristics of the gastrointestinal resistome in a cow‐to‐calf model and its environmental dissemination in a dairy production system

open access: yesiMeta, EarlyView.
This study revealed spatio‐temporal characteristics of gastrointestinal resistome in a cow‐to‐calf model and the pattern of their spread to the environment and offspring in the dairy production system. The gastrointestinal tract of dairy cows is a natural reservoir of resistomes and distinguished by gut sites and regions.
Shuai Liu   +19 more
wiley   +1 more source

Identification of 2 novel noncoding variants in patients with Diamond-Blackfan anemia syndrome by whole genome sequencing. [PDF]

open access: yesBlood Adv
Wen T   +13 more
europepmc   +1 more source

Gut microbiota and tuberculosis

open access: yesiMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu   +39 more
wiley   +1 more source

METTL5‐mediated 18S rRNA m6A modification enhances ribosome assembly and ABA response in Arabidopsis

open access: yesiMeta, EarlyView.
METTL5 catalyzes the N6‐methyladenosine (m6A) methylation at A1771 in 18S rRNA, a modification essential for its association with the ribosomal protein RPL24A, facilitating the assembly of 80S ribosome. This facilitates the translation of mRNAs encoding the detoxifying glutathione S‐transferase (GST) enzymes, thereby maintaining normal reactive oxygen ...
Ping Li   +5 more
wiley   +1 more source

Macrophage‐derived reactive oxygen species promote Salmonella aggresome formation contributing to bacterial antibiotic persistence

open access: yesiMeta, EarlyView.
In this study, we reveal that macrophage‐derived reactive oxygen species (ROS) can trigger the rapid formation of Salmonella aggresomes, which substantially contribute to the increased frequency of persisters induced by phagocytosis. Salmonella containing aggresomes exhibited a dormant phenotype characterized by reduced adenosine triphosphate (ATP ...
Xiao Chen   +11 more
wiley   +1 more source

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