Results 1 to 10 of about 169,665 (258)

A Small Regulatory RNA Generated from the malK 5′ Untranslated Region Targets Gluconeogenesis in Vibrio Species

mSphere, 2021
Juvenile pacific oysters have been subject in recent years to summer mortality episodes with deep economic consequences.
Xing Luo, Marick Esberard, Philippe Bouloc, Annick Jacq   +3 more
doaj   +3 more sources

Weight Change Alters the Small RNA Profile of Urinary Extracellular Vesicles in Obesity

Obesity Facts, 2022
Introduction: Various kidney diseases reportedly show different urinary extracellular vesicle (EV) RNA profiles. Although obesity is one of the main causes of chronic kidney disease, the expression pattern of urinary EV RNA in obesity is uncertain.
Dughyun Choi, Sewon Kim, Jeyoung Woo, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han, Sang Hyun Kim, Ho Chan Cho, Jong-Soo Choi, Yun-Ui Bae, Soon Hyo Kwon   +12 more
doaj   +1 more source

Developmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium

Cell Reports, 2023
Summary: The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic development in metazoans. However, it is currently unknown whether similar processes exist in unicellular eukaryotes. The ciliate Paramecium tetraurelia harbors
Therese Solberg, Victor Mason, Chundi Wang, Mariusz Nowacki   +3 more
doaj   +1 more source

An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes

Cell Reports, 2020
Summary: Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated regions (UTRs) to control gene expression. Using a comparative structural analysis, we examine the structure of 5′ UTRs at a global scale in the pathogenic ...
Dmitriy Ignatov, Karolis Vaitkevicius, Sylvain Durand, Laty Cahoon, Stefanie S. Sandberg, Xijia Liu, Birgitte H. Kallipolitis, Patrik Rydén, Nancy Freitag, Ciarán Condon, Jörgen Johansson   +10 more
doaj   +1 more source

Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]

PLoS Genetics, 2010
The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng, Paul Ryvkin, Fan Li, Isabelle Dragomir, Otto Valladares, Jamie Yang, Kajia Cao, Li-San Wang, Brian D Gregory   +8 more
doaj   +1 more source

microRNAs Mediated Regulation of the Ribosomal Proteins and its Consequences on the Global Translation of Proteins

Cells, 2021
Ribosomal proteins (RPs) are mostly derived from the energy-consuming enzyme families such as ATP-dependent RNA helicases, AAA-ATPases, GTPases and kinases, and are important structural components of the ribosome, which is a supramolecular ...
Abu Musa Md Talimur Reza, Yu-Guo Yuan
doaj   +1 more source

New Insight about of microRNAs & short interfering RNA in Treatment of COVID-19; a Narrative Review

Men's Health Journal, 2022
Since 31 December 2019, the coronavirus disease 2019 (COVID-19) resulted in a state of hyperinflammation syndrome and multiorgan failure. In areas with pandemic outbreaks, despite several emerging vaccines, supportive treatments to mitigate fatality ...
Mohammad Ali Salahshoor, Reza Mahjub
doaj   +1 more source

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Afar D. E. H., Audette M., Baniyash M., Berling B., Culic O., Elsen P., Felgner P. L., Fiddes J. C., Knapp W., Kolbinger F., Kuroki M., Kuroki M., Kuroki M., Lin S.-H., Lucas K., Margolis R. N., McCuaig K., Nap M., Neumaier M., Ng S. Y., Oikawa S., Oikawa S., Paxton R., Pelegrin A., Raskind W. H., Rojas M., Sambrook J. E., Schwarz K., Shively J. E., Skubitz K. M., Southern P. J., Thompson J. A., Thompson J. A., Turbide C., Tynan K., Watt S. M., Woodgett J. R., Zhou H.   +37 more
core   +5 more sources

SUMO-Modification of the La Protein Facilitates Binding to mRNA In Vitro and in Cells. [PDF]

PLoS ONE, 2016
The RNA-binding protein La is involved in several aspects of RNA metabolism including the translational regulation of mRNAs and processing of pre-tRNAs.
Venkatesh Kota, Gunhild Sommer, Chantal Durette, Pierre Thibault, Erna A van Niekerk, Jeffery L Twiss, Tilman Heise   +6 more
doaj   +1 more source

A Small Ligand That Selectively Binds to the G-quadruplex at the Human Vascular Endothelial Growth Factor Internal Ribosomal Entry Site and Represses the Translation

Frontiers in Chemistry, 2021
G-quadruplexes are believed to have important biological functions, so many small molecules have been screened or developed for targeting G-quadruplexes.
Xiao-Xia Hu, Xiao-Xia Hu, Sheng-Quan Wang, Shi-Quan Gan, Lei Liu, Ming-Qing Zhong, Meng-Hao Jia, Fei Jiang, Yan Xu, Chao-Da Xiao, Chao-Da Xiao, Xiang-Chun Shen, Xiang-Chun Shen   +12 more
doaj   +1 more source