Results 1 to 10 of about 4,997 (67)

PltRNAdb: Plant transfer RNA database

PLoS ONE, 2022
Transfer RNAs (tRNAs) are intermediate-sized non-coding RNAs found in all organisms that help translate messenger RNA into protein. Recently, the number of sequenced plant genomes has increased dramatically.
Morad M. Mokhtar, Achraf EL Allali
doaj   +3 more sources

Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture

eLife, 2023
Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the ‘transferome’) is unknown.
Sandipan Dasgupta, Daniella Y Dayagi, Gal Haimovich, Emanuel Wyler, Tsviya Olender, Robert H Singer, Markus Landthaler, Jeffrey E Gerst   +7 more
doaj   +1 more source

Exogenous RNA as a Regulatory Signal during a Plant’s Interaction with the Biotic Environment: An Evolutionary Perspective and Future Applications in Agriculture

Plants, 2021
Environmental RNAi (eRNAi) is a sequence-specific regulation of endogenous gene expression in a responsive organism by exogenous RNA. While exogenous RNA transfer between organisms of different kingdoms of life have been unambiguously identified in ...
Sergey Ivashuta, Alberto Iandolino, Greg Watson   +2 more
doaj   +1 more source

Myosin-Va-dependent cell-to-cell transfer of RNA from Schwann cells to axons. [PDF]

PLoS ONE, 2013
To better understand the role of protein synthesis in axons, we have identified the source of a portion of axonal RNA. We show that proximal segments of transected sciatic nerves accumulate newly-synthesized RNA in axons.
José R Sotelo, Lucía Canclini, Alejandra Kun, José R Sotelo-Silveira, Lei Xu, Horst Wallrabe, Aldo Calliari, Gonzalo Rosso, Karina Cal, John A Mercer   +9 more
doaj   +1 more source

Thinking Quantitatively of RNA-Based Information Transfer via Extracellular Vesicles: Lessons to Learn for the Design of RNA-Loaded EVs

Pharmaceutics, 2021
Extracellular vesicles (EVs) are 50–1000 nm vesicles secreted by virtually any cell type in the body. They are expected to transfer information from one cell or tissue to another in a short- or long-distance way. RNA-based transfer of information via EVs
Max Piffoux, Jeanne Volatron, Amanda K. A. Silva, Florence Gazeau   +3 more
doaj   +1 more source

Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]

PLoS ONE, 2017
Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse, Yuedong Yang, Jian Zhan, Jihua Wang, Yaoqi Zhou   +4 more
doaj   +1 more source

A novel mistranslating tRNA model in Drosophila melanogaster has diverse, sexually dimorphic effects

G3: Genes, Genomes, Genetics, 2022
Transfer RNAs (tRNAs) are the adaptor molecules required for reading the genetic code and producing proteins. Transfer RNA variants can lead to genome-wide mistranslation, the misincorporation of amino acids not specified by the standard genetic code ...
Joshua R Isaacson, Matthew D Berg, Brendan Charles, Jessica Jagiello, Judit Villén, Christopher J Brandl, Amanda J Moehring   +6 more
doaj   +1 more source

Tissue-specific differences in human transfer RNA expression. [PDF]

PLoS Genetics, 2006
Over 450 transfer RNA (tRNA) genes have been annotated in the human genome. Reliable quantitation of tRNA levels in human samples using microarray methods presents a technical challenge.
Kimberly A Dittmar, Jeffrey M Goodenbour, Tao Pan   +2 more
doaj   +1 more source

Liquid biopsy: an examination of platelet RNA obtained from head and neck squamous cell carcinoma patients for predictive molecular tumor markers

Exploration of Targeted Anti-tumor Therapy, 2023
Aim: Recently, a tumor cell-platelet interaction was identified in different tumor entities, resulting in a transfer of tumor-derived RNA into platelets, named further “tumor-educated platelets (TEP)”.
Lisa T. Huber, Johann M. Kraus, Jasmin Ezić, Amin Wanli, Marco Groth, Simon Laban, Thomas K. Hoffmann, Barbara Wollenberg, Hans A. Kestler, Cornelia Brunner   +9 more
doaj   +1 more source

Transfer RNA and human disease

Frontiers in Genetics, 2014
Pathological mutations in tRNA genes and tRNA processing enzymes are numerous and result in very complicated clinical phenotypes. Mitochondrial tRNA (mt-tRNA) genes are hotspots for pathological mutations and over 200 mt-tRNA mutations have been linked ...
Jamie A Abbott, Chris S Francklyn, Susan M Robey-Bond   +2 more
doaj   +1 more source