Results 71 to 80 of about 925,090 (301)

Non-Empirically Tuned Range-Separated DFT Accurately Predicts Both Fundamental and Excitation Gaps in DNA and RNA Nucleobases [PDF]

open access: yes, 2012
Using a non-empirically tuned range-separated DFT approach, we study both the quasiparticle properties (HOMO-LUMO fundamental gaps) and excitation energies of DNA and RNA nucleobases (adenine, thymine, cytosine, guanine, and uracil).
Foster, Michael E., Wong, Bryan M.
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Analysis of Mitochondrial Transfer RNA Mutations in Breast Cancer

open access: yesBalkan Journal of Medical Genetics, 2022
Damage of mitochondrial functions caused by mitochondrial DNA (mtDNA) pathogenic mutations had long been proposed to be involved in breast carcinogenesis. However, the detailed pathological mechanism remained deeply undetermined.
Ding H.J.   +4 more
doaj   +1 more source

RNAseq reveals hydrophobins that are involved in the adaptation of aspergillus nidulans to lignocellulose [PDF]

open access: yes, 2016
Background Sugarcane is one of the world’s most profitable crops. Waste steam-exploded sugarcane bagasse (SEB) is a cheap, abundant, and renewable lignocellulosic feedstock for the next-generation biofuels.
Brown, Neil Andrew   +7 more
core   +4 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Prebiotic chiral transfer from self-aminoacylating ribozymes may favor either handedness

open access: yesNature Communications
Modern life is essentially homochiral, containing D-sugars in nucleic acid backbones and L-amino acids in proteins. Since coded proteins are theorized to have developed from a prebiotic RNA World, the homochirality of L-amino acids observed in all known ...
Josh Kenchel   +10 more
doaj   +1 more source

The first mitochondrial genome for the subfamily Asopinae (Heteroptera: Pentatomidae) and its phylogenetic implications

open access: yesMitochondrial DNA. Part B. Resources, 2017
Here, we determined the complete mitogenome of Picromerus griseus, the first for the subfamily Asopinae. This mitochondrial genome contains 16,338 bp, with an A + T content of 71.69%, and contains 37 typical mitochondrial genes (13 protein-coding genes ...
Qing Zhao   +5 more
doaj   +1 more source

Charging State Analysis of Transfer RNA from an α-proteobacterium

open access: yesBio-Protocol, 2020
Transfer RNA (tRNA) is an essential link between the genetic code and proteins. During the process of translation, tRNA is charged with its cognate amino acid and delivers it to the ribosome, thus serving as a substrate of protein synthesis.
Liang Yin, Caroline Harwood
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Transfer RNA and Origins of RNA Interference

open access: yesFrontiers in Molecular Biosciences, 2021
Andrey Grigoriev
doaj   +1 more source

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