Results 51 to 60 of about 158,881 (313)
mBio, 2019 Positive-sense RNA viruses in the Tombusviridae family have genomes lacking a 5′ cap structure and prototypical 3′ polyadenylation sequence. Instead, these viruses utilize an extensive network of intramolecular RNA-RNA interactions to direct viral ...
Jesse D. Pyle +2 more
doaj +1 more source
Progress on the regulation of malignant biological behavior of glioma by HMGB1 gene
Chinese Journal of Contemporary Neurology and NeurosurgeryGlioma is often recurred after standard treatment due to its complex biological characteristics and the presence of glioma stem cells (GSCs). High -mobility group box 1 (HMGB1) can regulate the malignant progression of glioma through a variety of ways as
WANG Jun-cheng +4 more
doaj +1 more source
The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal [PDF]
, 2012 Transcription termination of the mRNA produced from the small (S) genome segment of Bunyamwera orthobunyavirus (BUNV) has previously been mapped to two cis-acting sequences located within the 5′ UTR using a virus-free replication assay.
Elliott, Richard Michael +5 more
core +1 more source
Cells, 2021 Ribosomal proteins (RPs) are mostly derived from the energy-consuming enzyme families such as ATP-dependent RNA helicases, AAA-ATPases, GTPases and kinases, and are important structural components of the ribosome, which is a supramolecular ...
Abu Musa Md Talimur Reza, Yu-Guo Yuan
doaj +1 more source
The role of TNRC6 proteins in gene silencing [PDF]
, 2013 Proteins of the GW182 family have recently emerged as key players in miRNAmediated gene silencing. They have been shown to interact with Argonaute proteins, components of the RISC and are assumed to mediate the repression in metazoa. Three paralogues are
Zipprich, Jakob Theophil
core +1 more source
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs
, 2010 Theis C, Janssen S, Giegerich R. Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs. In: Moulton V, Singh M, eds. Algorithms in Bioinformatics. 10th international workshop (WABI 2010), proceedings. Lecture Notes in Bioinformatics. Vol
Corinna Theis +7 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Computational discovery of animal small RNA genes and targets [PDF]
, 2007 Though recently discovered, small RNAs appear to play a wealth of regulatory roles, being involved in degradation of target mRNAs, translation silencing of target genes, chromatin remodeling and transposon silencing.
Gaidatzis, Dimosthenis
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Design of in vitro Transcribed mRNA Vectors for Research and Therapy
CHIMIA, 2019 The use of in vitro transcribed messenger RNA (ivt mRNA) for vaccination, gene therapy and cell reprograming has become increasingly popular in research and medicine.
Marina Tusup +5 more
doaj +1 more source