Secondary structure models of the 3′ untranslated regions of diverse R2 RNAs [PDF]
RNA, 2004 The RNA structure of the 3′ untranslated region (UTR) of the R2 retrotransposable element is recognized by the R2-encoded reverse transcriptase in a reaction called target primed reverse transcription (TPRT). To provide insight into structure–function relationships important for TPRT, we have created alignments that reveal the secondary structure for ...
Amy M, Ruschak +6 more
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Developmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium
Cell Reports, 2023 Summary: The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic development in metazoans. However, it is currently unknown whether similar processes exist in unicellular eukaryotes. The ciliate Paramecium tetraurelia harbors
Therese Solberg +3 more
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Regulatory RNAs: Have mRNA Untranslated Regions Joined the Party?
PLoS Medicine, 2008 Thomas Hughes and Pamela Jones discuss the implications of a new study on the 5' non-coding region of vascular endothelial growth factor mRNA and its influence on gene expression.
Hughes, T.A., Jones, P.F.
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RNA-protein interactions within the 3 ' untranslated region of vimentin mRNA [PDF]
Nucleic Acids Research, 1997 Several functions have been attributed to protein binding within the 3'untranslated region (3'UTR) of mRNA, including mRNA localization, stability, and translational repression. Vimentin is an intermediate filament protein whose 3'untranslated sequence is highly conserved between species.
Z E, Zehner +5 more
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Functional characterization of Ysh1p, the yeast endonuclease involved in 3" end processing and in transcription termination of RNA polymerase II transcripts [PDF]
, 2008 Eukaryotic RNA polymerase II (RNAP II) is involved in the synthesis of two major classes of transcripts: messenger RNAs (mRNAs) and small nuclear and small nucleolar RNAs.
Garas, Monika
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Evolutionary conservation of the AU-rich 3'untranslated region of messenger RNA. [PDF]
Proceedings of the National Academy of Sciences, 1994 AU-rich sequence motifs (specifically sequences containing reiterations of AUUUA) are found in the 3' untranslated region of mammalian mRNAs encoding cytokines, adhesion molecules, and protooncogenes. Because these AU-rich elements (3'AURE) have been observed to reduce the stability and translational efficiency of transcripts that contain them, and ...
M A, Asson-Batres +4 more
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mSphere, 2021 Juvenile pacific oysters have been subject in recent years to summer mortality episodes with deep economic consequences.
Xing Luo +3 more
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Profiling Alternative 3′ Untranslated Regions in Sorghum using RNA-seq Data
Frontiers in Genetics, 2020 Sorghum is an important crop widely used for food, feed, and fuel. Transcriptome-wide studies of 3′ untranslated regions (3′UTR) using regular RNA-seq remain scarce in sorghum, while transcriptomes have been characterized extensively using Illumina short-
Min Tu, Yin Li
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SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. [PDF]
PLoS Pathogens, 2011 SARS coronavirus (SCoV) nonstructural protein (nsp) 1, a potent inhibitor of host gene expression, possesses a unique mode of action: it binds to 40S ribosomes to inactivate their translation functions and induces host mRNA degradation.
Cheng Huang +5 more
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EZH2: A Crucial Competing Endogenous RNA in Cancer Research-A Scoping Review
Advanced Biomedical ResearchRecently, research on the competing endogenous RNAs (ceRNAs) in cancer has been in full swing, emphasizing their importance as critical RNAs in cancer progression.
Sadra Salehi-Mazandarani +3 more
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