Results 31 to 40 of about 158,881 (313)

A factor that specifically binds to the 5'‐untranslated region of encephalomyocarditis virus RNA [PDF]

FEBS Letters, 1990
A protein factor that specifically binds to the 5'‐untranslated region of encephalomyocarditis virus (EMCV) RNA has been found in extracts of ascites carcinoma Krebs‐2 cells. This was done using UV‐irradiation on extracts supplemented with in vitro synthesized 32P‐labelled transcripts followed by analysis of crosslinked proteins by SDS‐polyacrylamide ...
Borovjagin, A.V., Evstafieva, A.G., Ugarova, T.Yu., Shatsky, I.N.   +3 more
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Structural Components for Amplification of Positive and Negative Strand VEEV Splitzicons

Frontiers in Molecular Biosciences, 2018
RNA is a promising nucleic acid technology for both vaccines and therapeutics, and replicon RNA has gained traction as a next-generation RNA modality. Replicon RNA self-amplifies using a replicase complex derived from alphaviral non-structural proteins ...
Anna K. Blakney, Paul F. McKay, Robin J. Shattock   +2 more
doaj   +1 more source

Control of Listeria monocytogenes virulence by 5′-untranslated RNA

Trends in Microbiology, 2006
The Gram-positive bacterium Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. Expression of five of these factors has previously been shown to be subjected to post-transcriptional regulation as a result of their long 5'-untranslated region (5'-UTR).
Loh, E, Gripenland, J, Johansson, J
openaire   +3 more sources

Discovering non-coding RNA elements in Drosophila 3' untranslated regions [PDF]

International Journal of Bioinformatics Research and Applications, 2014
The Non-Coding RNA (ncRNA) elements in the 3' Untranslated Regions (3'-UTRs) are known to participate in the genes' post-transcriptional regulations. Inferring co-expression patterns of the genes through clustering these 3'-UTR ncRNA elements will provide invaluable insights for studying their biological functions. In this paper, we propose an improved
Cuncong Zhong, Justen Andrews, Shaojie Zhang 0001   +2 more
openaire   +4 more sources

Functions of the 5′- and 3′-untranslated regions of tobamovirus RNA

Virus Research, 2015
The tobamovirus genome is a 5'-m(7)G-capped RNA that carries a tRNA-like structure at its 3'-terminus. The genomic RNA serves as the template for both translation and negative-strand RNA synthesis. The 5'- and 3'-untranslated regions (UTRs) of the genomic RNA contain elements that enhance translation, and the 3'-UTR also contains the elements necessary
Tetsuya, Chujo, Kazuhiro, Ishibashi, Shuhei, Miyashita, Masayuki, Ishikawa   +3 more
openaire   +2 more sources

Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations

Nature Communications, 2020
G-quadruplexes (G4s) are secondary structures that can form in both DNA and RNA from guanine-rich sequences which are enriched in untranslated regions (UTRs). Here, Lee et al.
David S. M. Lee, Louis R. Ghanem, Yoseph Barash   +2 more
doaj   +1 more source

Transcription termination and antitermination of bacterial CRISPR arrays

eLife, 2020
A hallmark of CRISPR-Cas immunity systems is the CRISPR array, a genomic locus consisting of short, repeated sequences (‘repeats’) interspersed with short, variable sequences (‘spacers’). CRISPR arrays are transcribed and processed into individual CRISPR
Anne M Stringer, Gabriele Baniulyte, Erica Lasek-Nesselquist, Kimberley D Seed, Joseph T Wade   +4 more
doaj   +1 more source

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-seq and ESTs [PDF]

, 2014
The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct and complete annotation in addition to the underlying genomic sequence is particularly important when interpreting the results ...
Junfang Song, Geoffrey J Barton, Schurch Nicholas J., Brown, Sara J., Gordon G Simpson, Nicholas J Schurch, McLean, W. H. Irwin, Song Junfang, Simpson Gordon G., Sherstnev, Alexander, Brown Sara J., Alexander Sherstnev, Song, Junfang, McLean W. H. Irwin, Duc, Celine, Kate G Storey, Storey, Kate G., Schurch, Nicholas J., Cole Christian, Sherstnev Alexander, Simpson, Gordon G., Céline Duc, W H Irwin McLean, Cole, Christian; id_orcid, Christian Cole, Barton Geoffrey J., Sara J Brown, Duc Céline, Barton, Geoffrey J.; id_orcid, Storey Kate G.   +29 more
core   +1 more source

Tunable protein synthesis by transcript isoforms in human cells

eLife, 2016
Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated ...
Stephen N Floor, Jennifer A Doudna
doaj   +1 more source

Sequences at the 3′ Untranslated Region of Bamboo Mosaic Potexvirus RNA Interact with the Viral RNA-Dependent RNA Polymerase [PDF]

Journal of Virology, 2001
ABSTRACT The 3′ untranslated region (UTR) of bamboo mosaic potexvirus (BaMV) genomic RNA was found to fold into a series of stem-loop structures including a pseudoknot structure. These structures were demonstrated to be important for viral RNA replication and were believed to be recognized by the replicase (C.-P.
C Y, Huang, Y L, Huang, M, Meng, Y H, Hsu, C H, Tsai   +4 more
openaire   +2 more sources