Results 31 to 40 of about 907,910 (309)

Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]

PLoS Genetics, 2010
The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng, Paul Ryvkin, Fan Li, Isabelle Dragomir, Otto Valladares, Jamie Yang, Kajia Cao, Li-San Wang, Brian D Gregory   +8 more
doaj   +1 more source

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
I. M. Jones, Gould, EA, Tuplin, Andrew, Gould, E. A., A. Buckley, E. A. Gould, A. Tuplin, Tuplin, A., Jones, I. M., Jones, I. M. (Ian M.), Buckley, A., Gould, E., T. S. Gritsun, Jones, IM, Gritsun, T. S., Tuplin, A, Evans, DJ, Evans, David J., Gritsun, TS, D. J. Evans, Evans, D. J., Buckley, A   +21 more
core   +1 more source

Control of Listeria monocytogenes virulence by 5′-untranslated RNA

Trends in Microbiology, 2006
The Gram-positive bacterium Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. Expression of five of these factors has previously been shown to be subjected to post-transcriptional regulation as a result of their long 5'-untranslated region (5'-UTR).
Loh, E, Gripenland, J, Johansson, J
openaire   +3 more sources

Structural Components for Amplification of Positive and Negative Strand VEEV Splitzicons

Frontiers in Molecular Biosciences, 2018
RNA is a promising nucleic acid technology for both vaccines and therapeutics, and replicon RNA has gained traction as a next-generation RNA modality. Replicon RNA self-amplifies using a replicase complex derived from alphaviral non-structural proteins ...
Anna K. Blakney, Paul F. McKay, Robin J. Shattock   +2 more
doaj   +1 more source

Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]

, 2012
tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena, Turowski, Tomasz W., Karkusiewicz, Iwona, Kowal, J   +3 more
core   +1 more source

Discovering non-coding RNA elements in Drosophila 3' untranslated regions [PDF]

International Journal of Bioinformatics Research and Applications, 2014
The Non-Coding RNA (ncRNA) elements in the 3' Untranslated Regions (3'-UTRs) are known to participate in the genes' post-transcriptional regulations. Inferring co-expression patterns of the genes through clustering these 3'-UTR ncRNA elements will provide invaluable insights for studying their biological functions. In this paper, we propose an improved
Cuncong Zhong, Justen Andrews, Shaojie Zhang 0001   +2 more
openaire   +5 more sources

Kissing interaction between 3' noncoding and coding sequences is essential for porcine arterivirus RNA replication [PDF]

, 2002
We used an infectious cDNA clone of Porcine reproductive and respiratory syndrome virus (PRRSV) to investigate the presence of essential replication elements in the region of the genome encoding the structural proteins.
R. C. L. Olsthoorn, Rottier, P.J.M., J. J. M. Meulenberg, Olsthoorn, R.R.C.L., M. H. Verheije, P. J. M. Rottier, M. V. Kroese, Meulenberg, J.J.M., Verheije, M.H., Olsthoorn, R.C.L., Kroese, M.V.   +10 more
core   +1 more source

Functions of the 5′- and 3′-untranslated regions of tobamovirus RNA

Virus Research, 2015
The tobamovirus genome is a 5'-m(7)G-capped RNA that carries a tRNA-like structure at its 3'-terminus. The genomic RNA serves as the template for both translation and negative-strand RNA synthesis. The 5'- and 3'-untranslated regions (UTRs) of the genomic RNA contain elements that enhance translation, and the 3'-UTR also contains the elements necessary
Tetsuya, Chujo, Kazuhiro, Ishibashi, Shuhei, Miyashita, Masayuki, Ishikawa   +3 more
openaire   +2 more sources

A factor that specifically binds to the 5'‐untranslated region of encephalomyocarditis virus RNA [PDF]

FEBS Letters, 1990
A protein factor that specifically binds to the 5'‐untranslated region of encephalomyocarditis virus (EMCV) RNA has been found in extracts of ascites carcinoma Krebs‐2 cells. This was done using UV‐irradiation on extracts supplemented with in vitro synthesized 32P‐labelled transcripts followed by analysis of crosslinked proteins by SDS‐polyacrylamide ...
Borovjagin, A.V., Evstafieva, A.G., Ugarova, T.Yu., Shatsky, I.N.   +3 more
openaire   +2 more sources

Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations

Nature Communications, 2020
G-quadruplexes (G4s) are secondary structures that can form in both DNA and RNA from guanine-rich sequences which are enriched in untranslated regions (UTRs). Here, Lee et al.
David S. M. Lee, Louis R. Ghanem, Yoseph Barash   +2 more
doaj   +1 more source