Results 161 to 170 of about 870,257 (232)

Estimating the minimum antiretroviral adherence required for plasma HIV-1 RNA viral load suppression among people living with HIV who use unregulated drugs. [PDF]

AIDS, 2022
Stover S, Milloy MJ, Grant C, Fairbairn N, Socías ME.   +4 more
europepmc   +1 more source

The exosome TRAMPs on viral RNA [PDF]

Nature Reviews Molecular Cell Biology, 2016
openaire   +2 more sources

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source

Microbial Matryoshka: Addressing the Relationship between Pathogenic Flagellated Protozoans and Their RNA Viral Endosymbionts (Family Totiviridae). [PDF]

Vet Sci
Ibañez-Escribano A, Gomez-Muñoz MT, Mateo M, Fonseca-Berzal C, Gomez-Lucia E, Perez RG, Alunda JM, Carrion J.   +7 more
europepmc   +1 more source

Genetic diversity through social heterosis can increase virulence in RNA viral infections and cancer progression. [PDF]

R Soc Open Sci, 2021
Ebrahimi S, Nonacs P.
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Melatonin may decrease risk for and aid treatment of COVID-19 and other RNA viral infections. [PDF]

Open Heart, 2021
DiNicolantonio JJ, McCarty M, Barroso-Aranda J.   +2 more
europepmc   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Defining within-host SARS-CoV-2 RNA viral load kinetics during acute COVID-19 infection within different respiratory compartments and their respective associations with host infectiousness: a protocol for a systematic review and meta-analysis. [PDF]

BMJ Open
Pan D, Martin CA, Nazareth J, Sze S, Al-Oraibi A, Gogoi M, Grolmusova N, Divall P, Decker J, Fletcher E, Williams C, Hay J, Baggaley RF, Wyllie AL, Stephenson I, Gaillard E, Nellums LB, Clark TW, Van-Tam JN, Cowling BJ, Hollingsworth TD, Gray L, Barer M, Pareek M.   +23 more
europepmc   +1 more source

RNA viral loads of SARS-CoV-2 Alpha and Delta variants in nasopharyngeal specimens at diagnosis stratified by age, clinical presentation and vaccination status. [PDF]

J Infect, 2022
Costa R, Olea B, Bracho MA, Albert E, de Michelena P, Martínez-Costa C, González-Candelas F, Navarro D.   +7 more
europepmc   +1 more source