Results 91 to 100 of about 915,194 (208)

Single-Molecule FRET Studies of RNA Structural Rearrangements and RNA-RNA Interactions. [PDF]

Methods Mol Biol, 2022
Małecka EM, Hua B, Woodson SA.
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Emergent RNA-RNA interactions can promote stability in a facultative phototrophic endosymbiosis. [PDF]

Proc Natl Acad Sci U S A, 2021
Jenkins BH, Maguire F, Leonard G, Eaton JD, West S, Housden BE, Milner DS, Richards TA.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Correction: The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA-RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis. [PDF]

Oncogene, 2023
Li D, She J, Hu X, Zhang M, Sun R, Qin S.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

CLASH Analyst: A Web Server to Identify In Vivo RNA-RNA Interactions from CLASH Data. [PDF]

Noncoding RNA, 2022
Wu WS, Brown JS, Chen PH, Shiue SC, Lee DE, Lee HC.   +5 more
europepmc   +1 more source

Study of regulatory models of RNA in RNA-protein phase separation condensation

四川大学学报. 自然科学版
This modeling study aims to model the regulatory role of RNA in RNA-protein （PROT） phase separation condensation （PSC）. First， based on diffusion kinetics and Hill kinetics， a novel theoretical model for dynamic RNA-PROT PSC is proposed.
HAN Tuo-Di, GUO Xiu-Zhen, ZHAO Xin-Jun, DANG Yu-Jie   +3 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Nonstandard RNA/RNA interactions likely enhance folding and stability of segmented ribosomes. [PDF]

RNA, 2022
Rivas M, Fox GE.
europepmc   +1 more source