Results 241 to 250 of about 2,650,407 (299)

Dynamic Mapping of RNA-Binding Proteins During <i>Bacillus subtilis</i> Sporulation Using Orthogonal Organic Phase Separation. [PDF]

Bio Protoc
Kaboré T, Delan-Forino C.
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Protein kinase a regulates cyclooxygenase-2 expression through the RNA-binding proteins HuR and TTP. [PDF]

J Biol Chem
Adame-Garcia SR, Hoang TS, Tien Vo PT, Burghi V, Cervantes-Villagrana RD, Orduña-Castillo LB, Ramms DJ, Trejo J, Gutkind JS.   +8 more
europepmc   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3'UTR isoform diversity. [PDF]

Genome Biol
Gazzara MR, Cater T, Mallory MJ, Barash Y, Lynch KW.   +4 more
europepmc   +1 more source

Post-transcriptional control by RNA-binding proteins links local synaptic translation to schizophrenia genetic risk

Tamušauskaitė K, Wells PM, Bhinge A, Mill J, Clifton NE.   +4 more
europepmc   +1 more source

Spectrometry and Its Application for the Detection of RNA-Binding Proteins: Advancements, Techniques and Challenges. [PDF]

Anal Sci Adv
Moradi M, Farjami Z, Akbarin MM.
europepmc   +1 more source

GRASP: a modular toolkit for building synthetic pentatricopeptide repeat RNA-binding proteins. [PDF]

Nucleic Acids Res
Dennis M, Low SY, Viljoen A, Pullakhandam A, Colas des Francs-Small C, Campbell-Clause L, Bond CS, Small I, Kwok van der Giezen FM.   +8 more
europepmc   +1 more source

RNA-binding proteins mediate the maturation of chromatin topology during differentiation. [PDF]

Nat Cell Biol
Dehingia B, Milewska-Puchała M, Janowski M, Rafiee MR, Abbas M, Piotrowska A, Senge J, Blaut P, Walsh D, Severino J, Chaudhury D, Iqbal S, Montiel-Manriquez R, Jankowska S, Zare P, Huber W, Xu J, Casellas R, Zimmermann T, Dłotko P, Krijgsveld J, Pękowska A.   +21 more
europepmc   +1 more source