ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha+4 more
wiley +1 more source
Novel sofosbuvir derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective. [PDF]
Alrehaily A+4 more
europepmc +1 more source
RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase [PDF]
Jonathan Leis
openalex +1 more source
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu+9 more
wiley +1 more source
A fungal RNA-dependent RNA polymerase is a novel player in plant infection and cross-kingdom RNA interference. [PDF]
Cheng AP+8 more
europepmc +1 more source
Effect of estradiol on rat uterus DNA-dependent RNA polymerases. Studies on solubilized enzymes.
Jean‐Claude Courvalin+4 more
openalex +1 more source
Electron Microscopy Analysis of the Interaction between Escherichia coli DNA-Dependent RNA Polymerase and the Replicative Form of Phage fd DNA. 1. Mapping of the Binding Sites [PDF]
Paolo U. Giacomoni+2 more
openalex +1 more source
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah+9 more
wiley +1 more source
Prediction of single nucleotide polymorphisms of RNA dependent RNA polymerase for the potato leafroll virus using computational and experimental approaches. [PDF]
Aseel DG, Elmaghraby AM, El-Far A.
europepmc +1 more source