RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA [PDF]
MicroRNAs (miRNAs) integrate with Argonaut (Ago) to create the RNA-induced silencing complex, and regulate gene expression by silencing target mRNAs. RNA editing of miRNA may affect miRNA processing, assembly of the Ago complex and target mRNA binding ...
Yalei Cui+2 more
doaj +3 more sources
Critical role of backbone coordination in the mRNA recognition by RNA induced silencing complex [PDF]
Lizhe Zhu et al. use a quasi Markov State Model built from extensive molecular dynamics simulations to elucidate the dynamics of RISC-mRNA interactions. Their results provide further insight on how a target nucleotide is positioned before recognition by ...
Lizhe Zhu+5 more
doaj +2 more sources
Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence [PDF]
The exchange of small RNAs (sRNAs) between hosts and pathogens can lead to gene silencing in the recipient organism, a mechanism termed cross-kingdom RNAi (ck-RNAi).
Florian Dunker+10 more
doaj +2 more sources
RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Simon J Allison, Jo Milner
doaj +8 more sources
miR-7 is recruited to the high molecular weight RNA-induced silencing complex in CD8+ T cells upon activation and suppresses IL-2 signaling. [PDF]
Toivakka M+6 more
europepmc +3 more sources
In Arabidopsis thaliana, RNA-Induced Silencing Complex-Loading of MicroRNAs Plays a Minor Regulatory Role During Photomorphogenesis Except for miR163. [PDF]
Lakatos L, Groma G, Silhavy D, Nagy F.
europepmc +3 more sources
The origin and effect of small RNA signaling in plants [PDF]
Given their sessile condition, land plants need to integrate environmental cues rapidly and send signal throughout the organism to modify their metabolism accordingly. Small RNA (sRNA) molecules are among the messengers that plant cells use to carry such
Jean-Sébastien eParent+2 more
doaj +3 more sources
Expression of concern: 'RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA' (2015), by Cui Y et al. [PDF]
Open Biology editorial team.
europepmc +3 more sources
Is circulating exosome carry Staphylococcal nuclease domain-containing protein 1, a component of RNA-induced silencing complex? [PDF]
Shiragannavar VD+2 more
europepmc +2 more sources
Retraction: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui et al. [PDF]
Open Biology editorial team.
doaj +2 more sources