Results 131 to 140 of about 253,943 (166)

In Silico Development of a Targeted Small Interfering RNA (siRNA) Sequence to Silence Goblet Cell Mucin-5AC Overexpression in Cystic Fibrosis. [PDF]

Cureus
Ahluwalia J, Katakam A, Revuri N, Satish S.   +3 more
europepmc   +1 more source

Ribosomal protein RPL7A modulates lung adenocarcinoma progression via circRANBP17-UPF1-mediated SIRT6 degradation. [PDF]

Cell Mol Biol Lett
Zhu Y, Han J, Pan Y, Liu Y, Zhang Z, Chen H, Zhou S, Sun Z, Liu Y, Wang Q.   +9 more
europepmc   +1 more source

The efficacy of oligonucleotide-based gene therapeutics in gene silencing. [PDF]

Theranostics
Patra C, Hussein Z, Ace VD, Misnik EV, Rybalko DS, Salimova AA, Ereshko DS, Dubovichenko MV, Nour MAY, Drozd VS, Kolpashchikov DM.   +10 more
europepmc   +1 more source

One virus, many answers: Toward unlocking passion fruit's genetic secrets. [PDF]

Plant Physiol
Kumar J, Alok A.
europepmc   +1 more source

MicroRNA chemical modifications in post-transcriptional gene silencing and human diseases. [PDF]

Mol Ther Nucleic Acids
Alaei A, Kakumani PK.
europepmc   +1 more source

Gene expression silencing therapy in tumors, focus on gastrointestinal and genitourinary tumors. [PDF]

Front Immunol
El-Ghazzi N, Italiano A, Angeli E.
europepmc   +1 more source

Emerging roles of long non-coding RNAs in osteoarthritis: from molecular mechanisms to therapeutic opportunities. [PDF]

RNA Biol
Zhao Y, Zhang Y, Peng Y, Zheng Z, Li Q, Shen J, Wang H, Liu F.   +7 more
europepmc   +1 more source

Presence of phosphodiester backbone, but not nucleobases, in the guide's 3' terminal region is necessary for RISC loading and target cleavage in vitro and in vivo. [PDF]

Nucleic Acids Res
O'Reilly D, Furgal RC, Ross VM, Luu E, Gross KY, Hariharan V, Summers A, Cooper D, Allen S, Dahlke C, Rachid MO, Chan IL, Fakih HH, Alterman JF, Echeverria D, Watts JK, Khvorova A.   +16 more
europepmc   +1 more source

CircSipa1l1 modulates melanoma cell differentiation by activating the IGF2BP1-ARHGDIB axis and ERK signaling pathway. [PDF]

J Transl Med
Li BH, Liu L, Shi D, Wang XL, Meng TY, Xu XM, Zhai JL, He XJ, Wang GL, An TY, Jiang QL, Bi SX, Pan ZH, Zheng QS, Lu J, Li DF.   +15 more
europepmc   +1 more source