Results 191 to 200 of about 457,045 (298)

Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma

Advanced Science, EarlyView.
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang, Kun Shang, Lidong Gong, Qian Xie, Jianfei Sun, Meng Xu, Xunbin Wei, Zhaoheng Xie, Xinyu Liu, Hao Tang, Zhengren Xu, Wei Wang, Haihua Xiao, Zhiqiang Lin, Hongbin Han   +14 more
wiley   +1 more source

Splice it hot: How nuclear PP2A B'η regulates splicing fidelity by targeting the heat-stressed spliceosome. [PDF]

Plant Cell
Wang J.
europepmc   +1 more source

Faculty Opinions recommendation of ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing.

, 2014
Sarah A. Woodson, Hui-Ting Lee
openalex   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

Analysis of High Molecular Weight RNA-induced silencing complex (HMW-RISC) in CD8⁺ T cells identifies miR-7 as a modulator of T cell activation

, 2020
Matilda Toivakka, Katrina Gordon, Sujai Kumar, Rose Zamoyska, Amy H. Buck   +4 more
openalex   +1 more source

The 5′-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex [PDF]

, 2009
Ning Xu, Sofia Gkountela, Khalid Saeed, Göran Akusjärvi   +3 more
openalex   +1 more source

In Situ and Real‐Time Multi‐Modality Imaging Guided Orderly Triple‐Therapy of Tumors with a Multifunctional Nanodrug

Advanced Science, EarlyView.
A multifunctional AuNR@SiO2@MnO2@ DNA prodrugs (ASMD) nanodrug is designed to establish an in situ and real‐time photoacoustic (PA)/magnetic resonance (MR)/fluorescence (FL) multi‐modality imaging guided orderly photothermal therapy (PTT)/chemodynamic therapy (CDT)/gene therapy (GT) triple‐therapy of tumor.
Chaoyi Yang, Yuexuan Meng, Ying An, Jing Jia, Yuru Wang, Guangming Li, Yiran Li, Shan Wu, Chengyao Geng, Yunlong Chen, Huangxian Ju   +10 more
wiley   +1 more source

Efficient Virus-Induced Gene Silencing (VIGS) Method for Discovery of Resistance Genes in Soybean. [PDF]

Plants (Basel)
Deng K, Lu Z, Yang H, Chen S, Li C, Cao D, Wang H, Hao Q, Chen H, Shan Z.   +9 more
europepmc   +1 more source

The FGF13‐Caveolin‐1 Axis: A Key Player in the Pathogenesis of Doxorubicin‐ and D‐Galactose‐Induced Premature Cardiac Aging

Advanced Science, EarlyView.
The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen, Yuecheng Wu, Weijian Ye, Sihang Li, Junjie Zhu, Meifan Jiang, Zhicheng Hu, Gaoyong Cao, Xiaojing Yi, Fan Li, Zhouhao Tang, Xiaokun Li, Kwang Youl Lee, Litai Jin, Xu Wang, Weitao Cong   +15 more
wiley   +1 more source

Trans-Kingdom sRNA Silencing in <i>Sclerotinia sclerotiorum</i> for Crop Fungal Disease Management. [PDF]

Pathogens
Ouyang Y, Xia Y, Tang X, Qin L, Xia S.
europepmc   +1 more source