Results 31 to 40 of about 457,045 (298)

Tryptophan As a New Member of RNA‐Induced Silencing Complexes Prevents Colon Cancer Liver Metastasis

open access: greenAdvanced Science
AbstractEssential amino acids (EAA) and microRNAs (miRs) control biological activity of a cell. Whether EAA regulates the activity of miR has never been demonstrated. Here, as proof‐of‐concept, a tryptophan (Trp, an EAA) complex containing Argonaute 2 (Ago2) and miRs including miR‐193a (Trp/Ago2/miR‐193a) is identified.
Fangyi Xu   +11 more
openalex   +4 more sources

RISC in Development; A Review on RNA Induced Silencing Complex and its Contribution to Cellular Differentiation [PDF]

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2011
Messenger RNAs may be targeted by short 19-27 nt RNAs generally called Small none-coding RNAs (snRNAs), the role of miRNAs among other snRNAs has been more studied and is well known. Many researches show that all compartments of RISC, Proteins and miRNAs
Amirali Davoudpour
doaj   +3 more sources

Inhibiting MicroRNA function globally to target cancer: an emerging new scenario [PDF]

open access: yesWorld Cancer Research Journal, 2020
MicroRNA (miRNA) is an important class of small non-coding RNAs that act as post-transcriptional modulators of gene expression, and whose dysregulation has been implicated in various stages of cancer development. Although promising experimental evidences
G. La Rocca, M. Mauro
doaj   +1 more source

Author response: Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence

open access: gold, 2020
Florian Dunker   +10 more
openalex   +2 more sources

Development of a Viral RdRp-Assisted Gene Silencing System and Its Application in the Identification of Host Factors of Plant (+)RNA Virus

open access: yesFrontiers in Microbiology, 2021
Gene silencing induced by hairpin RNA or virus infection expression is one of the major tools in genetics studies in plants. However, when dealing with essential genes, virus-induced gene silencing (VIGS) and transgenic expression of hairpin RNA could ...
Wang Zhang   +6 more
doaj   +1 more source

Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

open access: yeseLife, 2021
In animal gonads, the PIWI-interacting RNA (piRNA) pathway guards genome integrity in part through the co-transcriptional gene silencing of transposon insertions.
Evelyn L Eastwood   +8 more
doaj   +1 more source

RNA interference approaches for plant disease control

open access: yesBioTechniques, 2020
Plant diseases caused by a variety of pathogens can have severe effects on crop plants and even plants in natural ecosystems. Despite many effective conventional approaches to control plant diseases, new, efficacious, environmentally sound and cost ...
Yen-Wen Kuo, Bryce W Falk
doaj   +1 more source

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