Results 31 to 40 of about 167,761 (271)
The Plant JournalSUMMARYRNA interference mediated via the action of micro RNAs (miRNAs) plays a pivotal role in developmental and stress response pathways. In the nucleus, plant miRNAs are generated by subsequent enzymatic cuts of the MIRNA precursors, having specific hairpin‐like secondary structures, to liberate the miRNA/miRNA* duplex.
Ágnes Dalmadi +4 more
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The 5′-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex [PDF]
Nucleic Acids Research, 2009 Human Adenovirus type 5 encodes two short RNA polymerase III transcripts, the virus-associated (VA) RNAI and VA RNAII, which can adopt stable hairpin structures that resemble micro-RNA precursors.
Ning Xu +3 more
semanticscholar +2 more sources
RISC in Development; A Review on RNA Induced Silencing Complex and its Contribution to Cellular Differentiation [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2011 Messenger RNAs may be targeted by short 19-27 nt RNAs generally called Small none-coding RNAs (snRNAs), the role of miRNAs among other snRNAs has been more studied and is well known. Many researches show that all compartments of RISC, Proteins and miRNAs
Amirali Davoudpour
doaj +3 more sources
Inhibiting MicroRNA function globally to target cancer: an emerging new scenario [PDF]
World Cancer Research Journal, 2020 MicroRNA (miRNA) is an important class of small non-coding RNAs that act as post-transcriptional modulators of gene expression, and whose dysregulation has been implicated in various stages of cancer development. Although promising experimental evidences
G. La Rocca, M. Mauro
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Author response: Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence
, 2020 Florian Dunker +10 more
openaire +2 more sources
SND1, a component of RNA-induced silencing complex, is up-regulated in human colon cancers and implicated in early stage colon carcinogenesis. [PDF]
Cancer Research, 2007 Naoto Tsuchiya +5 more
semanticscholar +2 more sources
Frontiers in Microbiology, 2021 Gene silencing induced by hairpin RNA or virus infection expression is one of the major tools in genetics studies in plants. However, when dealing with essential genes, virus-induced gene silencing (VIGS) and transgenic expression of hairpin RNA could ...
Wang Zhang +6 more
doaj +1 more source
CCR4-NOT Deadenylates mRNA Associated with RNA-Induced Silencing Complexes in Human Cells [PDF]
Molecular and Cellular Biology, 2010 MicroRNAs (miRNAs) repress gene expression posttranscriptionally by inhibiting translation and by expediting deadenylation so as to trigger rapid mRNA decay. Their regulatory influence is mediated by the protein components of the RNA-induced silencing complex (RISC), which deliver miRNAs and siRNAs to their mRNA targets.
X. Piao +3 more
semanticscholar +4 more sources