Results 41 to 50 of about 253,943 (166)
Author response: Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence
, 2020 Florian Dunker +10 more
openalex +2 more sources
RNA interference approaches for plant disease control
BioTechniques, 2020 Plant diseases caused by a variety of pathogens can have severe effects on crop plants and even plants in natural ecosystems. Despite many effective conventional approaches to control plant diseases, new, efficacious, environmentally sound and cost ...
Yen-Wen Kuo, Bryce W Falk
doaj +1 more source
eLife, 2021 In animal gonads, the PIWI-interacting RNA (piRNA) pathway guards genome integrity in part through the co-transcriptional gene silencing of transposon insertions.
Evelyn L Eastwood +8 more
doaj +1 more source
Decision letter: Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence
, 2020 Michael J. Axtell
openalex +2 more sources
Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons
Cells, 2022 RNA-binding proteins (RBPs) play important roles in modulating miRNA-mediated mRNA target repression. Argonaute2 (Ago2) is an essential component of the RNA-induced silencing complex (RISC) that plays a central role in silencing mechanisms via small non ...
Christian Barbato +8 more
doaj +1 more source
CCR4-NOT Deadenylates mRNA Associated with RNA-Induced Silencing Complexes in Human Cells [PDF]
Molecular and Cellular Biology, 2010 MicroRNAs (miRNAs) repress gene expression posttranscriptionally by inhibiting translation and by expediting deadenylation so as to trigger rapid mRNA decay. Their regulatory influence is mediated by the protein components of the RNA-induced silencing complex (RISC), which deliver miRNAs and siRNAs to their mRNA targets.
X. Piao +3 more
semanticscholar +3 more sources
Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation. [PDF]
PLoS Genetics, 2007 Mammalian Argonaute proteins (EIF2C1-4) play an essential role in RNA-induced silencing. Here, we show that the loss of eIF2C2 (Argonaute2 or Ago2) results in gastrulation arrest, ectopic expression of Brachyury (T), and mesoderm expansion. We identify a
Reid S Alisch +4 more
doaj +1 more source
Using RNAi in the treatment of cardiovascular diseases - therapeutics based on siRNA overview
Journal of Education, Health and Sport, 2022 RNA interference (RNAi) discovered in the 1990s by Fire and Mello plays a role in silencing gene function. One type of RNAi is siRNA, which is a double-stranded molecule of 20-25 base pairs.
Barbara Rusinowska
doaj +1 more source
RNA duplexes in transcriptional regulation
Biomolecular Concepts, 2010 Transcriptional regulation by small RNA molecules, including small interfering RNA and microRNA, has emerged as an important gene expression modulator.
Swaminathan Sanjay +3 more
doaj +1 more source
The roles of microRNA in redox metabolism and exercise-mediated adaptation
Journal of Sport and Health Science, 2020 MicroRNAs (miRs) are small regulatory RNA transcripts capable of post-transcriptional silencing of mRNA messages by entering a cellular bimolecular apparatus called RNA-induced silencing complex.
Ferenc Torma +7 more
doaj +1 more source