Results 61 to 70 of about 457,045 (298)
Genetics and Molecular Biology, 2007 The RNA interference (RNAi) technique is a recent technology that uses double-stranded RNA molecules to promote potent and specific gene silencing. The application of this technique to molecular biology has increased considerably, from gene function ...
Tiago Campos Pereira +5 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Understanding and Remediating Open-Source License Incompatibilities in the PyPI Ecosystem [PDF]
arXiv, 2023 The reuse and distribution of open-source software must be in compliance with its accompanying open-source license. In modern packaging ecosystems, maintaining such compliance is challenging because a package may have a complex multi-layered dependency graph with many packages, any of which may have an incompatible license.
arxiv
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2017 Background/Aims: Long non-coding RNAs (lncRNAs) are key players in the development and progression of human cancers. The lncRNA XIST (X-inactive specific transcript) has been shown to be upregulated in human non-small cell lung cancer (NSCLC); however ...
Haoyou Wang +8 more
doaj +1 more source
Synaptotagmin 11 interacts with components of the RNA‐induced silencing complex RISC in clonal pancreatic β‐cells [PDF]
FEBS Letters, 2014 Synaptotagmins are two C2 domain‐containing transmembrane proteins. The function of calcium‐sensitive members in the regulation of post‐Golgi traffic has been well established whereas little is known about the calcium‐insensitive isoforms constituting half of the protein family. Novel binding partners of synaptotagmin 11 were identified in β‐cells.
Anne Dominique Lajoix +11 more
openaire +2 more sources
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2014 Pepino mosaic virus (PepMV) (family Alphaflexiviridae, genus Potexvirus) is a mechanically transmitted tomato pathogen that, over the last decade, has evolved from emerging to endemic worldwide.
Matthaios M. Mathioudakis +4 more
doaj +1 more source
Enzymatically produced pools of canonical and Dicer-substrate siRNA molecules display comparable gene silencing and antiviral activities against herpes simplex virus. [PDF]
PLoS ONE, 2012 RNA interference (RNAi)-based sequence-specific gene silencing is applied to identify gene function and also possesses great potential for inhibiting virus replication both in animals and plants.
Alesia Romanovskaya +5 more
doaj +1 more source
Microbiology Spectrum, 2023 Some insect viruses encode suppressors of RNA interference (RNAi) to counteract the antiviral RNAi pathway. However, it is unknown whether Bombyx mori cytoplasmic polyhedrosis virus (BmCPV) encodes an RNAi suppressor. In this study, the presence of viral
Jun Pan +8 more
doaj +1 more source