Results 71 to 80 of about 457,045 (298)

Hybrid Precoding in Cooperative Millimeter Wave Networks [PDF]

open access: yesarXiv, 2020
In this paper, we study the performance of cooperative millimeter wave (mmWave) networks with hybrid precoding architectures. Considering joint transmissions and BS silence strategy, we propose hybrid precoding algorithms which minimize the sum power consumption of the base stations (BSs), for both fully- and partially-connected hybrid precoding (FHP ...
arxiv  

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

RNA processing errors triggered by cadmium and integrator complex disruption are signals for environmental stress

open access: yesBMC Biology, 2019
Background Adaptive responses to stress are essential for cell and organismal survival. In metazoans, little is known about the impact of environmental stress on RNA homeostasis.
Cheng-Wei Wu   +5 more
doaj   +1 more source

A Mathematical Framework for Kinetochore-Driven Activation Feedback in the Mitotic Checkpoint [PDF]

open access: yes, 2017
Proliferating cells properly divide into their daughter cells through a process that is mediated by kinetochores, protein-complexes that assemble at the centromere of each sister chromatid. Each kinetochore has to establish a tight bipolar attachment to the spindle apparatus before sister-chromatid separation is initiated.
arxiv   +1 more source

Data Based Identification and Prediction of Nonlinear and Complex Dynamical Systems [PDF]

open access: yesPhysics Reports 644, 1-76 (2016), 2017
The problem of reconstructing nonlinear and complex dynamical systems from measured data or time series is central to many scientific disciplines including physical, biological, computer, and social sciences, as well as engineering and economics. In this paper, we review the recent advances in this forefront and rapidly evolving field, aiming to cover ...
arxiv   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Thermodynamic control of small RNA-mediated gene silencing

open access: yesFrontiers in Genetics, 2012
Small interfering RNAs (siRNAs) and microRNAs (miRNAs) are crucial regulators of posttranscriptional gene silencing, which is referred to as RNA interference (RNAi) or RNA silencing.
Kumiko eUi-Tei   +3 more
doaj   +1 more source

Titration and hysteresis in epigenetic chromatin silencing [PDF]

open access: yes2013 Phys. Biol. 10 036005, 2012
Epigenetic mechanisms of silencing via heritable chromatin modifications play a major role in gene regulation and cell fate specification. We consider a model of epigenetic chromatin silencing in budding yeast and study the bifurcation diagram and characterize the bistable and the monostable regimes.
arxiv   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Silence is Sweeter Than Speech: Self-Supervised Model Using Silence to Store Speaker Information [PDF]

open access: yesarXiv, 2022
Self-Supervised Learning (SSL) has made great strides recently. SSL speech models achieve decent performance on a wide range of downstream tasks, suggesting that they extract different aspects of information from speech. However, how SSL models store various information in hidden representations without interfering is still poorly understood.
arxiv  

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