Results 81 to 90 of about 253,943 (166)

Research Progress in Plant Antiviral Silencing: Argonaute-Centered Perspective

open access: yesGuangdong nongye kexue
In the long-term evolution process, plants have evolved multi-layered defense mechanisms to sense and respond to the invasion of harmful organisms such as viruses, to adapt to the adverse environment and avoid attacks from harmful organisms.
Zhaoyun WANG, Jinli XIONG, Xiu WANG
doaj   +1 more source

CMV2b-Dependent Regulation of Host Defense Pathways in the Context of Viral Infection

open access: yesViruses, 2018
RNA silencing (or RNA interference, RNAi) plays direct roles in plant host defenses against viruses. Viruses encode suppressors of RNAi (VSRs) to counteract host antiviral defenses.
Jian-Hua Zhao   +4 more
doaj   +1 more source

NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo

open access: yesFrontiers in Cellular Neuroscience, 2014
microRNAs (miRNAs) are major regulators of protein synthesis in the brain. A major goal is to identify changes in miRNA expression underlying protein synthesis-dependent forms of synaptic plasticity such as long-term potentiation (LTP). Previous analyses
Balagopal ePai   +12 more
doaj   +1 more source

C-terminal tagging impairs AGO2 function

open access: yesRNA Biology
MicroRNA-mediated gene silencing is a conserved mechanism of post-transcriptional gene regulation across metazoans. It depends on base pairing between small RNAs and mRNAs, and on protein complexes including the RNA-induced silencing complex (RISC ...
Kunal M. Shah   +7 more
doaj   +1 more source

A proteomic study of TAR-RNA binding protein (TRBP)-associated factors

open access: yesCell & Bioscience, 2011
Background The human TAR RNA-binding protein, TRBP, was first identified and cloned based on its high affinity binding to the small hairpin trans-activation responsive (TAR) RNA of HIV-1.
Chi Ya-Hui   +2 more
doaj   +1 more source

MicroRNAs in the Stressed Heart: Sorting the Signal from the Noise

open access: yesCells, 2014
The short noncoding RNAs, known as microRNAs, are of undisputed importance in cellular signaling during differentiation and development, and during adaptive and maladaptive responses of adult tissues, including those that comprise the heart.
Scot J. Matkovich
doaj   +1 more source

Virus-induced gene silencing

open access: yes浙江大学学报. 农业与生命科学版, 2008
The term virus-induced gene silencing' (VIGS) was first used to describe the phenomenon of recovery from virus infection, a natural plant antiviral mechanism, which recently has been exploited as a genetic technique involving recombinant viruses with a ...
XU You-ping   +4 more
doaj   +1 more source

The biogenesis, regulation and functions of transitive siRNA in plants

open access: yesActa Biochimica et Biophysica Sinica
Small RNA (sRNA)-mediated RNA interference (RNAi) is a sequence-specific gene silencing mechanism that modulates gene expression in eukaryotes. As core molecules of RNAi, various sRNAs are encoded in the plant
Tan Huijun, Liu Yuelin, Guo Hongwei
doaj   +1 more source

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