Results 91 to 100 of about 867,422 (305)

Identification of proteins binding coding and non-coding human RNAs using protein microarrays

BMC Genomics, 2012
Background The regulation and function of mammalian RNAs has been increasingly appreciated to operate via RNA-protein interactions. With the recent discovery of thousands of novel human RNA molecules by high-throughput RNA sequencing, efficient methods ...
Siprashvili Zurab, Webster Dan E, Kretz Markus, Johnston Danielle, Rinn John L, Chang Howard Y, Khavari Paul A   +6 more
doaj   +1 more source

iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution [PDF]

, 2011
Julian König, Kathi Zarnack, Gregor Rot, Tomaž Curk, Melis Kayikci, Blaž Zupan, Daniel J. Turner, Nicholas M. Luscombe, Jernej Ule   +8 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Balancing Act: The Viral–Host Battle over RNA Binding Proteins

Viruses
A defining feature of a productive viral infection is the co-opting of host cell resources for viral replication. Despite the host repertoire of molecular functions and biological counter measures, viruses still subvert host defenses to take control of ...
Yahaira Bermudez, David Hatfield, Mandy Muller   +2 more
doaj   +1 more source

Effects of RNA structure and salt concentration on the affinity and kinetics of interactions between pentatricopeptide repeat proteins and their RNA ligands.

PLoS ONE, 2018
Pentatricopeptide repeat (PPR) proteins are helical repeat proteins that bind specific RNA sequences via modular 1-repeat:1-nucleotide interactions. Binding specificity is dictated, in part, by hydrogen bonds between the amino acids at two positions in ...
James J McDermott, Bryce Civic, Alice Barkan   +2 more
doaj   +1 more source

Microscopy data: interaction of the gene iscub with RNA polymerase II clusters during early zebrafish embryo development

, 2021
Irina Mamontova, Agnieszka Pancholi, Roshan Prizak, Lennart Hilbert   +3 more
openalex   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A comparative analysis of topological domain callers over RNA-associated interactome

BMC Bioinformatics
Background Topological domains (TADs) are consecutive genomic locations with denser local interactions to a certain extent, and they are important for cellular gene expression control and modulation.
Tuna Alaygut, Emre Sefer
doaj   +1 more source

Global transcriptome responses including small RNAs during mixed‐species interactions with methicillin‐resistant Staphylococcus aureus and Pseudomonas aeruginosa [PDF]

, 2016
Christine L. Miller, Tricia A. Van Laar, Tsute Chen, S. L. Rajasekhar Karna, Ping Chen, Tao You, Kai P. Leung   +6 more
openalex   +1 more source

Stricturing Crohn’s disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions [PDF]

, 2023
Pranab K. Mukherjee, Quang Tam Nguyen, Jiannan Li, Shuai Zhao, Stephen M. Christensen, Gail West, Jyotsna Chandra, Ilyssa O. Gordon, Sinan Lin, Jie Wang, Ren Mao, D. Czarnecki, Carla Rayan, Prerna Kotak, Thomas Plesec, Samir Lal, Thomas Fabre, Shoh Asano, Kathryn Bound, Kevin M. Hart, Chanyoung Park, Robert Martinez, Ken Dower, Thomas A. Wynn, Shaomin Hu, Nayden G. Naydenov, Martin Decaris, Scott Turner, Stefan D. Holubar, Scott R. Steele, Claudio Fiocchi, Andrei I. Ivanov, Kellie M. Kravarik, Florian Rieder   +33 more
openalex   +1 more source