Results 11 to 20 of about 867,422 (305)

Detecting RNA-RNA interactions in E. coli using a modified CLASH method [PDF]

open access: yesBMC Genomics, 2017
Background Bacterial small regulatory RNAs (sRNAs) play important roles in sensing environment changes through sRNA-target mRNA interactions. However, the current strategy for detecting sRNA-mRNA interactions usually combines bioinformatics prediction ...
Tao Liu   +7 more
doaj   +2 more sources

Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti

open access: yesCell Reports, 2023
Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective ...
Sarah Hélène Merkling   +11 more
doaj   +1 more source

Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum [version 2; peer review: 2 approved]

open access: yesOpen Research Europe, 2022
Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of ...
Jessica Bryant, Sebastian Baumgarten
doaj   +1 more source

Accelerating the BPMax Algorithm for RNA-RNA Interaction [PDF]

open access: yes2021 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW), 2021
RNA-RNA interactions (RRI) play an important role in various biological processes such as gene transcription, and are known to play a critical role in diseases such as cancer and Alzheimer’s, necessitating efficient computational tools. To date, RRI programs like BPMax were developed and optimized by hand, and this is prone to human error, and costly ...
Chiranjeb Mondal, Sanjay V. Rajopadhye
openaire   +1 more source

Combinatorics of RNA–RNA interaction [PDF]

open access: yesJournal of Mathematical Biology, 2011
RNA-RNA binding is an important phenomenon observed for many classes of non-coding RNAs and plays a crucial role in a number of regulatory processes. Recently several MFE folding algorithms for predicting the joint structure of two interacting RNA molecules have been proposed.
Li, Thomas J X, Reidys, Christian
openaire   +5 more sources

Topology of RNA-RNA Interaction Structures [PDF]

open access: yesJournal of Computational Biology, 2012
40 pages 15 ...
Jørgen E. Andersen   +3 more
openaire   +6 more sources

Fast prediction of RNA-RNA interaction [PDF]

open access: yesAlgorithms for Molecular Biology, 2009
Abstract Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its ...
Salari, Raheleh   +2 more
openaire   +6 more sources

Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut

open access: yesiScience, 2020
Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling   +9 more
doaj   +1 more source

RILogo: visualizing RNA–RNA interactions [PDF]

open access: yesBioinformatics, 2012
Abstract Summary: With the increasing amount of newly discovered non-coding RNAs, the interactions between RNA molecules become an increasingly important aspect for characterizing their functionality. Many computational tools have been developed to predict the formation of duplexes between two RNAs, either based on single sequences or ...
Peter Menzel   +2 more
openaire   +3 more sources

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