Results 31 to 40 of about 436,281 (168)
Toxicology Reports, 2022 Formalin-fixed paraffin-embedded (FFPE) samples are the only remaining biological archive for many toxicological and clinical studies, yet their use in genomics has been limited due to nucleic acid damage from formalin fixation.
Michael D. Cannizzo +3 more
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PLoS ONE, 2019 The wealth of information deliverable from transcriptome sequencing (RNA-seq) is significant, however current applications for variant detection still remain a challenge due to the complexity of the transcriptome.
Modupeore O Adetunji +3 more
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Probe Region Expression Estimation for RNA-Seq Data for Improved Microarray Comparability. [PDF]
PLoS ONE, 2015 Rapidly growing public gene expression databases contain a wealth of data for building an unprecedentedly detailed picture of human biology and disease.
Karolis Uziela, Antti Honkela
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The Comparison between Bulk RNA-seq and Ssingle-cell RNA-seq
Journal of Physics: Conference Series, 2021 Abstract Bulk RNA-seq and single cell RNA-seq (Sc-RNA) seq are two well-known methods and are broadly used in biology areas. Even though the two ways are all starting from the mRNA level to do the transcriptional analysis, many differences still show in them, but the differences which are critical for researchers to judge and consider ...
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trumpet: transcriptome-guided quality assessment of m6A-seq data
BMC Bioinformatics, 2018 Background Methylated RNA immunoprecipitation sequencing (MeRIP-seq or m6A-seq) has been extensively used for profiling transcriptome-wide distribution of RNA N6-Methyl-Adnosine methylation.
Teng Zhang +3 more
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COEX-Seq: Convert a Variety of Measurements of Gene Expression in RNA-Seq [PDF]
Genomics & Informatics, 2018 Next generation sequencing (NGS), a high-throughput DNA sequencing technology, is widely used for molecular biological studies. In NGS, RNA-sequencing (RNA-Seq), which is a short-read massively parallel sequencing, is a major quantitative transcriptome ...
Sang Cheol Kim +2 more
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Dissecting intratumoral myeloid cell plasticity by single cell RNA‐seq
Cancer Medicine, 2019 Tumor‐infiltrating myeloid cells are the most abundant leukocyte population within tumors. Molecular cues from the tumor microenvironment promote the differentiation of immature myeloid cells toward an immunosuppressive phenotype.
Qianqian Song +19 more
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BioengineeringRNA sequencing (RNA-seq) has emerged as a prominent resource for transcriptomic analysis due to its ability to measure gene expression in a highly sensitive and accurate manner.
Farhana Manzoor +2 more
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Polyribosomal RNA-Seq reveals the decreased complexity and diversity of the Arabidopsis translatome.
PLoS ONE, 2015 Recent RNA-seq studies reveal that the transcriptomes in animals and plants are more complex than previously thought, leading to the inclusion of many more splice isoforms in annotated genomes. However, it is possible that a significant proportion of the
Xingtan Zhang +4 more
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Statistical Modeling of RNA-Seq Data
Statistical Science, 2011 Recently, ultra high-throughput sequencing of RNA (RNA-Seq) has been developed as an approach for analysis of gene expression. By obtaining tens or even hundreds of millions of reads of transcribed sequences, an RNA-Seq experiment can offer a comprehensive survey of the population of genes (transcripts) in any sample of interest.
Salzman, Julia +2 more
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