Results 51 to 60 of about 591,228 (346)
Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma [PDF]
, 2018 Table summarizing the RNA-seq results. Differential gene expression results in BAP1-knockdown compared to control OCM-1A cells are shown from the RNA-seq data.
Chen, Xuhua +5 more
core +4 more sources
Simultaneous generation of many RNA-seq libraries in a single reaction [PDF]
, 2015 Although RNA-seq is a powerful tool, the considerable time and cost associated with library construction has limited its utilization for various applications.
Bhattacharyya, Roby P. +15 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
COEX-Seq: Convert a Variety of Measurements of Gene Expression in RNA-Seq [PDF]
Genomics & Informatics, 2018 Next generation sequencing (NGS), a high-throughput DNA sequencing technology, is widely used for molecular biological studies. In NGS, RNA-sequencing (RNA-Seq), which is a short-read massively parallel sequencing, is a major quantitative transcriptome ...
Sang Cheol Kim +2 more
doaj +1 more source
Improving RNA-Seq Precision with MapAl [PDF]
Frontiers in Genetics, 2012 With currently available RNA-Seq pipelines, expression estimates for most genes are very noisy. We here introduce MapAl, a tool for RNA-Seq expression profiling that builds on the established programs Bowtie and Cufflinks. In the post-processing of RNA-Seq reads, it incorporates gene models already at the stage of read alignment, increasing the number ...
Paweł P Łabaj +4 more
openaire +3 more sources
Comparison of reproducibility, accuracy, sensitivity, and specificity of miRNA quantification platforms [PDF]
, 2019 Given the increasing interest in their use as disease biomarkers, the establishment of reproducible, accurate, sensitive, and specific platforms for microRNA (miRNA) quantification in biofluids is of high priority.
Barczak, Andrea J +8 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Probe Region Expression Estimation for RNA-Seq Data for Improved Microarray Comparability. [PDF]
PLoS ONE, 2015 Rapidly growing public gene expression databases contain a wealth of data for building an unprecedentedly detailed picture of human biology and disease.
Karolis Uziela, Antti Honkela
doaj +1 more source
Near-optimal RNA-Seq quantification [PDF]
, 2015 We present a novel approach to RNA-Seq quantification that is near optimal in speed and accuracy. Software implementing the approach, called kallisto, can be used to analyze 30 million unaligned paired-end RNA-Seq reads in less than 5 minutes on a ...
Bray, Nicolas +3 more
core +1 more source