Results 11 to 20 of about 2,497,031 (299)
Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia [PDF]
Endocrinology and Metabolism, 2021 Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with statin and ezetimibe therapy, and ...
Brian Tomlinson +3 more
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Thermodynamics of RNA–RNA binding [PDF]
Bioinformatics, 2006 Abstract Background: Reliable prediction of RNA–RNA binding energies is crucial, e.g. for the understanding on RNAi, microRNA–mRNA binding and antisense interactions. The thermodynamics of such RNA–RNA interactions can be understood as the sum of two energy contributions: (1) the energy necessary to ‘open’ the binding site and (2) the ...
Mückstein, Ulrike +5 more
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Molecular identification of peste des petits ruminants virus in wild goat and domestic small ruminants by real-time -PCR technique in Erbil-Iraq [PDF]
Iraqi Journal of Veterinary Sciences, 2017 In July 2010 outbreak was occurred in wild goat in Barzan, Sherwin mizzen and Mergasur in Kurdistan Region- Iraq. There were over 2700 deaths (both young and adult) during the period of July 2010 to October 2011.
E.P. Candlan, F.P. Khoran, L. Hana
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CircCLTH promotes skeletal muscle development and regeneration
Epigenetics, 2022 Buffalo holds an excellent potential for beef production, and circRNA plays an important role in regulating myogenesis. However, the regulatory mechanism of circRNAs during buffalo skeletal muscle development has not been fully explored.
Mengjie Chen +12 more
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Disease Models & Mechanisms, 2022 The cellular level of TDP-43 (also known as TARDBP) is tightly regulated; increases or decreases in TDP-43 have deleterious effects in cells. The predominant mechanism responsible for the regulation of the level of TDP-43 is an autoregulatory negative ...
Miriam Pacetti +7 more
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Exploration of Medicine, 2023 m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato +10 more
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Acknowledgement to Reviewers of Non-Coding RNA in 2018
Non-Coding RNA, 2019 Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Non-Coding RNA Editorial Office
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Bone & Joint Research, 2023 Aims: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA.
Haokun Mo +7 more
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Nanocircular RNAs for RNA interference [PDF]
Nucleic Acids Symposium Series, 2008 We designed and synthesized dumbbell-shaped nanocircular RNAs for RNA interference applications, which consist of a stem and two loops(1). RNA dumbbells are specifically recognized and cleaved by the human Dicer enzyme, and are thus transformed into double-stranded RNA in cells, although this RNA is resistant to degradation in serum.
Hiroshi, Abe +4 more
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Acknowledgement to Reviewers of Non-Coding RNA in 2016
Non-Coding RNA, 2017 The editors of Non‐Coding RNA would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...]
Non-Coding RNA Editorial Office
doaj +1 more source