Results 11 to 20 of about 2,322,564 (290)

Combinatorics of RNA–RNA interaction [PDF]

open access: yesJournal of Mathematical Biology, 2011
RNA-RNA binding is an important phenomenon observed for many classes of non-coding RNAs and plays a crucial role in a number of regulatory processes. Recently several MFE folding algorithms for predicting the joint structure of two interacting RNA molecules have been proposed.
Li, Thomas J X, Reidys, Christian
openaire   +5 more sources

Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia [PDF]

open access: yesEndocrinology and Metabolism, 2021
Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with statin and ezetimibe therapy, and ...
Brian Tomlinson   +3 more
doaj   +1 more source

Thermodynamics of RNA–RNA binding [PDF]

open access: yesBioinformatics, 2006
Abstract Background: Reliable prediction of RNA–RNA binding energies is crucial, e.g. for the understanding on RNAi, microRNA–mRNA binding and antisense interactions. The thermodynamics of such RNA–RNA interactions can be understood as the sum of two energy contributions: (1) the energy necessary to ‘open’ the binding site and (2) the ...
Mückstein, Ulrike   +5 more
openaire   +3 more sources

Molecular identification of peste des petits ruminants virus in wild goat and domestic small ruminants by real-time -PCR technique in Erbil-Iraq [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2017
In July 2010 outbreak was occurred in wild goat in Barzan, Sherwin mizzen and Mergasur in Kurdistan Region- Iraq. There were over 2700 deaths (both young and adult) during the period of July 2010 to October 2011.
E.P. Candlan, F.P. Khoran, L. Hana
doaj   +1 more source

CircCLTH promotes skeletal muscle development and regeneration

open access: yesEpigenetics, 2022
Buffalo holds an excellent potential for beef production, and circRNA plays an important role in regulating myogenesis. However, the regulatory mechanism of circRNAs during buffalo skeletal muscle development has not been fully explored.
Mengjie Chen   +12 more
doaj   +1 more source

Physiological tissue-specific and age-related reduction of mouse TDP-43 levels is regulated by epigenetic modifications

open access: yesDisease Models & Mechanisms, 2022
The cellular level of TDP-43 (also known as TARDBP) is tightly regulated; increases or decreases in TDP-43 have deleterious effects in cells. The predominant mechanism responsible for the regulation of the level of TDP-43 is an autoregulatory negative ...
Miriam Pacetti   +7 more
doaj   +1 more source

m6 RNA methylation: an emerging common target in the immune response to cancer and severe acute respiratory syndrome-coronavirus-2 infection

open access: yesExploration of Medicine, 2023
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato   +10 more
doaj   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2018

open access: yesNon-Coding RNA, 2019
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages

open access: yesBone & Joint Research, 2023
Aims: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA.
Haokun Mo   +7 more
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B.   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy