Results 21 to 30 of about 2,860,779 (318)

RNA helicases in RNA decay [PDF]

open access: yesBiochemical Society Transactions, 2018
RNA molecules have the tendency to fold into complex structures or to associate with complementary RNAs that exoribonucleases have difficulties processing or degrading. Therefore, degradosomes in bacteria and organelles as well as exosomes in eukaryotes have teamed-up with RNA helicases.
Khemici, Vanessa, Linder, Patrick
openaire   +5 more sources

Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors [PDF]

open access: yes, 2023
Preadenylated single-stranded DNA ligation adaptors are essential reagents in many next generation RNA sequencing library preparation protocols. These oligonucleotides can be adenylated enzymatically or chemically.
Watts, Jonathan K   +4 more
core   +2 more sources

m6 RNA methylation: an emerging common target in the immune response to cancer and severe acute respiratory syndrome-coronavirus-2 infection

open access: yesExploration of Medicine, 2023
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato   +10 more
doaj   +1 more source

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]

open access: yes, 2010
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Andrzej Dziembowski   +3 more
core   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2018

open access: yesNon-Coding RNA, 2019
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]

open access: yes, 2012
tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena   +3 more
core   +1 more source

Extracellular RNAs as communicators in cardiovascular disease: a narrative review [PDF]

open access: yesExRNA, 2022
Background and Objective: Cardiovascular disease (CVD) is a leading cause of death in industrialized countries. It consists of different etiologies and has linked to other types of diseases (e.g., diabetes, renal failure). Thus, understanding the disease
Mirolyuba Ilieva, Shizuka Uchida
doaj   +1 more source

An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]

open access: yes, 2007
RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid   +4 more
core   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2016

open access: yesNon-Coding RNA, 2017
The editors of Non‐Coding RNA would like to express their sincere gratitude to the following  reviewers for assessing manuscripts in 2016.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages

open access: yesBone & Joint Research, 2023
Aims: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA.
Haokun Mo   +7 more
doaj   +1 more source

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