Nanocircular RNAs for RNA interference [PDF]
Nucleic Acids Symposium Series, 2008 We designed and synthesized dumbbell-shaped nanocircular RNAs for RNA interference applications, which consist of a stem and two loops(1). RNA dumbbells are specifically recognized and cleaved by the human Dicer enzyme, and are thus transformed into double-stranded RNA in cells, although this RNA is resistant to degradation in serum.
Hiroshi, Abe +4 more
openaire +2 more sources
Bone & Joint Research, 2023 Aims: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA.
Haokun Mo +7 more
doaj +1 more source
Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B. +4 more
core +1 more source
Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
, 2013 OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes. While RprA activates rpoS for translation, OxyS
Callaghan, Anastasia +9 more
core +1 more source
Acknowledgement to Reviewers of Non-Coding RNA in 2016
Non-Coding RNA, 2017 The editors of Non‐Coding RNA would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...]
Non-Coding RNA Editorial Office
doaj +1 more source
Prevalence of HEV infection markers in Chinese blood donors: a meta-analysis
Zhongguo shuxue zazhi, 2023 Objective To analyze the serological markers and RNA prevalence of HEV infection in Chinese voluntary blood donors in different regions of China, so as to provide basis for the necessity of HEV screening and the formulation of screening strategies for ...
Yuena XIE +4 more
doaj +1 more source
Evaluation of the LncRNA TMPO AS-1 Expression Level in Melanoma Tissues in Comparison to Paired Normal Marginal Tissues [PDF]
Middle East Journal of Cancer, 2023 Background: Long noncoding RNA (lncRNA) is recognized as an essential controller of gene expression and other activities of the cells. Additionally, lncRNAs have a critical role in the progression and growth of human malignancies, like melanoma.
Habib Zarredar +6 more
doaj +1 more source
Acknowledgement to Reviewers of Non-Coding RNA in 2017
Non-Coding RNA, 2018 Peer review is an essential part in the publication process, ensuring that Non-Coding RNA maintains high quality standards for its published papers.[...]
Non-Coding RNA Editorial Office
doaj +1 more source
Automated immunohistochemical assessment ability to evaluate estrogen and progesterone receptor status compared with quantitative reverse transcription-polymerase chain reaction in breast carcinoma patients [PDF]
Journal of Pathology and Translational Medicine, 2021 Background This study aimed to investigate the capability of an automated immunohistochemical (IHC) evaluation of hormonal receptor status in breast cancer patients compared to a well-validated quantitative reverse transcription–polymerase chain reaction
Taesung Jeon, Aeree Kim, Chungyeul Kim
doaj +1 more source
Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells [PDF]
, 2018 Schwann cells are key players in neuro-regeneration: They sense "alarm" signals released by degenerating nerve terminals and differentiate toward a proregenerative phenotype, with phagocytosis of nerve debris and nerve guidance.
Duregotti, E +10 more
core +1 more source