Results 11 to 20 of about 4,010,897 (309)
Thermodynamics of RNA–RNA binding [PDF]
Abstract Background: Reliable prediction of RNA–RNA binding energies is crucial, e.g. for the understanding on RNAi, microRNA–mRNA binding and antisense interactions. The thermodynamics of such RNA–RNA interactions can be understood as the sum of two energy contributions: (1) the energy necessary to ‘open’ the binding site and (2) the ...
Mückstein, Ulrike +5 more
openaire +3 more sources
Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia [PDF]
Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with statin and ezetimibe therapy, and ...
Brian Tomlinson +3 more
doaj +1 more source
Molecular identification of peste des petits ruminants virus in wild goat and domestic small ruminants by real-time -PCR technique in Erbil-Iraq [PDF]
In July 2010 outbreak was occurred in wild goat in Barzan, Sherwin mizzen and Mergasur in Kurdistan Region- Iraq. There were over 2700 deaths (both young and adult) during the period of July 2010 to October 2011.
E.P. Candlan, F.P. Khoran, L. Hana
doaj +1 more source
CircCLTH promotes skeletal muscle development and regeneration
Buffalo holds an excellent potential for beef production, and circRNA plays an important role in regulating myogenesis. However, the regulatory mechanism of circRNAs during buffalo skeletal muscle development has not been fully explored.
Mengjie Chen +12 more
doaj +1 more source
RNA-Puzzles Round IV:3D structure predictions of four ribozymes and two aptamers [PDF]
International audienceRNA-Puzzles is a collective endeavor dedicated to the advancement and improvement of RNA 3D structure prediction. With agreement from crystallographers, the RNA structures are predicted by various groups before the publication of ...
Adamiak, Ryszard W. +49 more
core +5 more sources
The cellular level of TDP-43 (also known as TARDBP) is tightly regulated; increases or decreases in TDP-43 have deleterious effects in cells. The predominant mechanism responsible for the regulation of the level of TDP-43 is an autoregulatory negative ...
Miriam Pacetti +7 more
doaj +1 more source
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato +10 more
doaj +1 more source
Acknowledgement to Reviewers of Non-Coding RNA in 2018
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Non-Coding RNA Editorial Office
doaj +1 more source
Cellular mRNAs access second ORFs using a novel amino acid sequence-dependent coupled translation termination-reinitiation mechanism [PDF]
Polycistronic transcripts are considered rare in the human genome. Initiation of translation of internal ORFs of eukaryotic genes has been shown to use either leaky scanning or highly structured IRES regions to access initiation codons.
Croft, Wayne D. +4 more
core +1 more source

