Results 41 to 50 of about 768,957 (268)

Evaluation of the LncRNA TMPO AS-1 Expression Level in Melanoma Tissues in Comparison to Paired Normal Marginal Tissues [PDF]

Middle East Journal of Cancer, 2023
Background: Long noncoding RNA (lncRNA) is recognized as an essential controller of gene expression and other activities of the cells. Additionally, lncRNAs have a critical role in the progression and growth of human malignancies, like melanoma.
Habib Zarredar, Milad Asadi, Dariush Shanehbandi, Venus Zafari, Soghra Bornodeli, Zahra Soleimani, Shahram Ghasembaglou   +6 more
doaj   +1 more source

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354), Jack O Phillips, Anastasia J Callaghan, Vincent, H., Andrew R. Pickford (485355), Adam J Roberts, Louise E. Butt (485353), Stone, Carlanne, Charlotte E. Mardle (485352), Henderson, Charlotte, Adam J. Roberts (485350), Pickford, Andy, Carlanne M Stone, Roberts, Adam J., Butt, Louise, Charlotte A Henderson, Louise E Butt, Anastasia J. Callaghan (485356), Helen A Vincent, Charlotte E Mardle, Callaghan, Anastasia, Carlanne M. Stone (485351), Phillips, Jack, Jack O. Phillips (485348), Charlotte A. Henderson (485349), Gowers, Darren, Mardle, C., Andrew R Pickford, Helen A. Vincent (485347), Darren M Gowers   +29 more
core   +1 more source

An improved in vivo tethering assay with single molecule FISH reveals that a nematode Nanos enhances reporter expression and mRNA stability

, 2021
Robust methods are critical for testing the in vivo regulatory mechanism of RNA binding proteins. Here we report improvement of a protein–mRNA tethering assay to probe the function of an RNA binding protein in its natural context within the C.
Kimble, Judith, Lynch, Tina R., Aoki, Scott T., Doenier, Jonathan   +3 more
core   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2017

Non-Coding RNA, 2018
Peer review is an essential part in the publication process, ensuring that Non-Coding RNA maintains high quality standards for its published papers.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Automated immunohistochemical assessment ability to evaluate estrogen and progesterone receptor status compared with quantitative reverse transcription-polymerase chain reaction in breast carcinoma patients [PDF]

Journal of Pathology and Translational Medicine, 2021
Background This study aimed to investigate the capability of an automated immunohistochemical (IHC) evaluation of hormonal receptor status in breast cancer patients compared to a well-validated quantitative reverse transcription–polymerase chain reaction
Taesung Jeon, Aeree Kim, Chungyeul Kim
doaj   +1 more source

A hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B [PDF]

, 2008
The genome of hepatitis C virus (HCV) contains cis-acting replication elements (CREs) comprised of RNA stem-loop structures located in both the 5' and 3' non-coding regions (NCR), and in the NS5B coding sequence.
Diviney, Sinéad, Elliot, R., Evans, David John, Evans, D., Armstrong, V, Tuplin, Andrew, Evans, D.J., Struthers, Madeleine, Struthers, M., Elliott, Richard M., Diviney, S., Tuplin, A., Armstrong, V., Struthers, M, Simmonds, Peter, Elliott, Richard Michael, Armstrong, Victoria, Tuplin, A, Evans, David J., Simmonds, P., Diviney, S, Elliott, R.M., Simmonds, P   +22 more
core   +1 more source

Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone

Bone & Joint Research, 2022
Aims: Osteoarthritis (OA) is a common degenerative joint disease. The osteocyte transcriptome is highly relevant to osteocyte biology. This study aimed to explore the osteocyte transcriptome in subchondral bone affected by OA.
Jun Zhou, Zhiyi He, Jiarui Cui, Xiaoling Liao, Hui Cao, Yo Shibata, Takashi Miyazaki, Jiaming Zhang   +7 more
doaj   +1 more source

Cooperativity and Interdependency between RNA Structure and RNA–RNA Interactions [PDF]

Non-Coding RNA, 2021
Complex RNA–RNA interactions are increasingly known to play key roles in numerous biological processes from gene expression control to ribonucleoprotein granule formation. By contrast, the nature of these interactions and characteristics of their interfaces, especially those that involve partially or wholly structured RNAs, remain elusive.
Ilias Skeparnias, Jinwei Zhang
openaire   +3 more sources

Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses:Implications for virus evolution and host persistence [PDF]

, 2004
Discrete RNA secondary and higher-order structures, typically local in extent, play a fundamental role in RNA virus replication. Using new bioinformatics analysis methods, we have identified genome-scale ordered RNA structure (GORS) in many genera and ...
Evans, David J, Simmonds, Peter, Tuplin, Andrew, Tuplin, A, Evans, DJ, Simmonds, P   +5 more
core   +1 more source

RNA-Catalyzed RNA Ligation on an External RNA Template [PDF]

Chemistry & Biology, 2002
Variants of the hc ligase ribozyme, which catalyzes ligation of the 3' end of an RNA substrate to the 5' end of the ribozyme, were utilized to evolve a ribozyme that catalyzes ligation reactions on an external RNA template. The evolved ribozyme catalyzes the joining of an oligonucleotide 3'-hydroxyl to the 5'-triphosphate of an RNA hairpin molecule ...
McGinness, Kathleen E, Joyce, Gerald F
openaire   +2 more sources