Breast Cancer Prevention: Current Approaches and Future Directions
The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential
Edward R. Sauter
doaj +1 more source
Extracellular RNAs as communicators in cardiovascular disease: a narrative review [PDF]
Background and Objective: Cardiovascular disease (CVD) is a leading cause of death in industrialized countries. It consists of different etiologies and has linked to other types of diseases (e.g., diabetes, renal failure). Thus, understanding the disease
Mirolyuba Ilieva, Shizuka Uchida
doaj +1 more source
Domain orientation in the RNA helicase YxiN and the role of conformational changes for RNA unwinding [PDF]
The RNA helicase YxiN from Bacillus subtilis is a member of the family of DEAD box proteins. YxiN is able to unwind RNA double strands in an ATP-dependent manner. The ability to catalyse RNA rearrangement is in vivo presumably necessary for the bacterial
Karow, Anne R.
core +1 more source
Investigating therapeutic efficacy of dacarbazine and temozolomide, alone and in combination with BRAF(V600E) siRNA in A375 human melanoma cell line [PDF]
Objective(s): Melanoma is one of the most aggressive and deadly skin cancers. Despite advances, effective melanoma treatment is challenging, often requiring a shift from individual therapies to combination approaches.
Fatemeh Tabandeh +3 more
doaj +1 more source
Estimate and determinants of SARS-CoV-2 RNA clearance time among non-severe COVID-19 patients
Objectives: To estimate SARS-CoV-2 RNA clearance time among non-severe COVID-19 patients and explore factors associated with delayed negative conversion.
Mohammed A Aljunaid +3 more
doaj +1 more source
Identification of novel components of Trypanosoma brucei editosomes [PDF]
The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome proteins in Trypanosoma brucei.
Schnaufer, Achim; id_orcid +6 more
core +1 more source
Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’ [PDF]
The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts.
Matthias Schaefer +2 more
doaj +1 more source
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs [PDF]
Theis C, Janssen S, Giegerich R. Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs. In: Moulton V, Singh M, eds. Algorithms in Bioinformatics. 10th international workshop (WABI 2010), proceedings. Lecture Notes in Bioinformatics. Vol
Corinna Theis +7 more
core +1 more source
Identification of RNAs Engaged in Direct RNA-RNA Interaction with a Long Non-Coding RNA
The growing role attributed nowadays to long non-coding RNAs (lncRNA) in physiology and pathophysiology makes it crucial to characterize their interactome by identifying their molecular partners, DNA, proteins and/or RNAs. The latter can interact with lncRNA through networks involving proteins, but they can also be engaged in direct RNA/RNA ...
Jacq, Audrey +6 more
openaire +3 more sources

