Results 51 to 60 of about 768,957 (268)

Clinical study of real-time polymerase chain reaction test kit for SARS-CoV-2 ribonucleic acids detection

open access: yesФармакоэкономика, 2022
Objective: development and validation of a reverse transcription polymerase chain reaction (RT-PCR) test kit for SARS-CoV-2 ribonucleic acids (RNA) qualitative detection adapted for using with automated station for RNA extraction.Material and methods ...
M. Yu. Dmitryukova   +3 more
doaj   +1 more source

Extracellular RNAs as communicators in cardiovascular disease: a narrative review [PDF]

open access: yesExRNA, 2022
Background and Objective: Cardiovascular disease (CVD) is a leading cause of death in industrialized countries. It consists of different etiologies and has linked to other types of diseases (e.g., diabetes, renal failure). Thus, understanding the disease
Mirolyuba Ilieva, Shizuka Uchida
doaj   +1 more source

Topology of RNA-RNA Interaction Structures [PDF]

open access: yesJournal of Computational Biology, 2012
40 pages 15 ...
Jørgen E. Andersen   +3 more
openaire   +6 more sources

RNA Chemistry for RNA Biology

open access: yesCHIMIA, 2019
Advances in the chemical synthesis of RNA have opened new possibilities to address current questions in RNA biology. Access to site-specifically modified oligoribonucleotides is often a pre-requisite for RNA chemical-biology projects. Driven by the enormous research efforts for development of oligonucleotide therapeutics, a wide range of ...
Rothlisberger, Pascal   +2 more
openaire   +5 more sources

Fast prediction of RNA-RNA interaction [PDF]

open access: yesAlgorithms for Molecular Biology, 2009
Abstract Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its ...
Salari, Raheleh   +2 more
openaire   +6 more sources

RT-PCR detection of SARS-CoV-2 in nasopharyngeal and salivary specimens: contribution of alternative collection systems and extraction processes to cope with mass screening. Interpretation of low viral loads

open access: yesJournal of Laboratory Medicine, 2022
Due to massive screening of the persistent coronavirus SARS-CoV-2, supply difficulties emerged for swabs and extraction reagents leading to test alternative choices.
Robinet Sylvain   +7 more
doaj   +1 more source

Domain orientation in the RNA helicase YxiN and the role of conformational changes for RNA unwinding [PDF]

open access: yes, 2010
The RNA helicase YxiN from Bacillus subtilis is a member of the family of DEAD box proteins. YxiN is able to unwind RNA double strands in an ATP-dependent manner. The ability to catalyse RNA rearrangement is in vivo presumably necessary for the bacterial
Karow, Anne R.
core   +1 more source

The mutual interaction of glycolytic enzymes and RNA in post-transcriptional regulation

open access: yes, 2022
Wegener M, Dietz K-J. The mutual interaction of glycolytic enzymes and RNA in post-transcriptional regulation. RNA . 2022.About three decades ago, researchers suggested that metabolic enzymes participate in cellular processes that are unrelated to their ...
Dietz, Karl-Josef   +3 more
core   +1 more source

Trim25 is an RNA-specific activator of Lin28a/TuT4-mediated uridylation [PDF]

open access: yes, 2014
RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated
Nowak, Jakub S.   +14 more
core   +1 more source

Breast Cancer Prevention: Current Approaches and Future Directions

open access: yesEuropean Journal of Breast Health, 2018
The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential
Edward R. Sauter
doaj   +1 more source

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