Results 51 to 60 of about 3,067,802 (311)

An improved in vivo tethering assay with single molecule FISH reveals that a nematode Nanos enhances reporter expression and mRNA stability

open access: yes, 2021
Robust methods are critical for testing the in vivo regulatory mechanism of RNA binding proteins. Here we report improvement of a protein–mRNA tethering assay to probe the function of an RNA binding protein in its natural context within the C.
Kimble, Judith   +3 more
core   +1 more source

RNA as Multitude/RNA as One [PDF]

open access: yesChemistry & Biology, 2003
In the configurations formed by RNA and its ions there are structural possibilities not yet realized; some are hinted at in new work on the binding of an amino acid analog.
openaire   +2 more sources

Clinical study of real-time polymerase chain reaction test kit for SARS-CoV-2 ribonucleic acids detection

open access: yesФармакоэкономика, 2022
Objective: development and validation of a reverse transcription polymerase chain reaction (RT-PCR) test kit for SARS-CoV-2 ribonucleic acids (RNA) qualitative detection adapted for using with automated station for RNA extraction.Material and methods ...
M. Yu. Dmitryukova   +3 more
doaj   +1 more source

RNA Chemistry for RNA Biology

open access: yesCHIMIA, 2019
Advances in the chemical synthesis of RNA have opened new possibilities to address current questions in RNA biology. Access to site-specifically modified oligoribonucleotides is often a pre-requisite for RNA chemical-biology projects. Driven by the enormous research efforts for development of oligonucleotide therapeutics, a wide range of ...
Rothlisberger, Pascal   +2 more
openaire   +5 more sources

Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses:Implications for virus evolution and host persistence [PDF]

open access: yes, 2004
Discrete RNA secondary and higher-order structures, typically local in extent, play a fundamental role in RNA virus replication. Using new bioinformatics analysis methods, we have identified genome-scale ordered RNA structure (GORS) in many genera and ...
Evans, David J   +5 more
core   +1 more source

Fast prediction of RNA-RNA interaction [PDF]

open access: yesAlgorithms for Molecular Biology, 2009
Abstract Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its ...
Salari, Raheleh   +2 more
openaire   +7 more sources

RT-PCR detection of SARS-CoV-2 in nasopharyngeal and salivary specimens: contribution of alternative collection systems and extraction processes to cope with mass screening. Interpretation of low viral loads

open access: yesJournal of Laboratory Medicine, 2022
Due to massive screening of the persistent coronavirus SARS-CoV-2, supply difficulties emerged for swabs and extraction reagents leading to test alternative choices.
Robinet Sylvain   +7 more
doaj   +1 more source

Topology of RNA-RNA Interaction Structures [PDF]

open access: yesJournal of Computational Biology, 2012
40 pages 15 ...
Jørgen E. Andersen   +3 more
openaire   +7 more sources

Domain orientation in the RNA helicase YxiN and the role of conformational changes for RNA unwinding [PDF]

open access: yes, 2010
The RNA helicase YxiN from Bacillus subtilis is a member of the family of DEAD box proteins. YxiN is able to unwind RNA double strands in an ATP-dependent manner. The ability to catalyse RNA rearrangement is in vivo presumably necessary for the bacterial
Karow, Anne R.
core   +1 more source

Breast Cancer Prevention: Current Approaches and Future Directions

open access: yesEuropean Journal of Breast Health, 2018
The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential
Edward R. Sauter
doaj   +1 more source

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