Domain orientation in the RNA helicase YxiN and the role of conformational changes for RNA unwinding [PDF]
, 2010 The RNA helicase YxiN from Bacillus subtilis is a member of the family of DEAD box proteins. YxiN is able to unwind RNA double strands in an ATP-dependent manner. The ability to catalyse RNA rearrangement is in vivo presumably necessary for the bacterial
Karow, Anne R.
core +1 more source
Trim25 is an RNA-specific activator of Lin28a/TuT4-mediated uridylation [PDF]
, 2014 RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated
Nowak, Jakub S. +14 more
core +1 more source
Breast Cancer Prevention: Current Approaches and Future Directions
European Journal of Breast Health, 2018 The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential
Edward R. Sauter
doaj +1 more source
RNA as Multitude/RNA as One [PDF]
Chemistry & Biology, 2003 In the configurations formed by RNA and its ions there are structural possibilities not yet realized; some are hinted at in new work on the binding of an amino acid analog.
openaire +2 more sources
Identification of novel components of Trypanosoma brucei editosomes [PDF]
, 2003 The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome proteins in Trypanosoma brucei.
Schnaufer, Achim; id_orcid +6 more
core +1 more source
Investigating therapeutic efficacy of dacarbazine and temozolomide, alone and in combination with BRAF(V600E) siRNA in A375 human melanoma cell line [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Melanoma is one of the most aggressive and deadly skin cancers. Despite advances, effective melanoma treatment is challenging, often requiring a shift from individual therapies to combination approaches.
Fatemeh Tabandeh +3 more
doaj +1 more source
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs [PDF]
, 2010 Theis C, Janssen S, Giegerich R. Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs. In: Moulton V, Singh M, eds. Algorithms in Bioinformatics. 10th international workshop (WABI 2010), proceedings. Lecture Notes in Bioinformatics. Vol
Corinna Theis +7 more
core +2 more sources
Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’ [PDF]
Open Biology, 2017 The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts.
Matthias Schaefer +2 more
doaj +1 more source
Estimate and determinants of SARS-CoV-2 RNA clearance time among non-severe COVID-19 patients
Journal of Family Medicine and Primary Care, 2022 Objectives: To estimate SARS-CoV-2 RNA clearance time among non-severe COVID-19 patients and explore factors associated with delayed negative conversion.
Mohammed A Aljunaid +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source