Results 1 to 10 of about 6,663,585 (252)

Identification of long noncoding RNA [PDF]

Poultry Science
Long non-coding RNAs ( lncRNAs ) are known to regulate skeletal muscle development in mammals, but their roles and potential as genetic markers in chickens remain largely unknown.
Yaohua Li, Jiahao Li, Siyu Guo, Xinyi Zheng, Wanxi He, Zihan Sun, Bolin Cai   +6 more
doaj   +2 more sources

Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Due to diagnosis of gastric cancer in advanced stages as well as its poor prognosis, finding biomarkers is essential. In this study, using the TCGA RNAseq data of gastric cancer patients, we evaluated the diagnostic value of lncRNAs that ...
Mahmoud Ghanei, Arash Poursjeikhani, Azadeh Aarabi, Negin Taghehchian, Mohammad Reza Abbaszadegan   +4 more
doaj   +1 more source

LINC00174 Suppresses Non-Small Cell Lung Cancer Progression by Up-Regulating LATS2 via Sponging miR-31-5p [PDF]

Cell Journal, 2022
Objective: Dysregulation of long non-coding RNAs (lncRNAs) is associated with the progression of non-small cell lung cancer (NSCLC). This study aimed to investigate the role of long intergenic non-protein coding RNA 174 (LINC00174) in NSCLC. Materials
Xueling Cheng, Mali Sha, Wenjin Jiang, Linjing Chen, Meihua Song   +4 more
doaj   +1 more source

Evaluation of the LncRNA TMPO AS-1 Expression Level in Melanoma Tissues in Comparison to Paired Normal Marginal Tissues [PDF]

Middle East Journal of Cancer, 2023
Background: Long noncoding RNA (lncRNA) is recognized as an essential controller of gene expression and other activities of the cells. Additionally, lncRNAs have a critical role in the progression and growth of human malignancies, like melanoma.
Habib Zarredar, Milad Asadi, Dariush Shanehbandi, Venus Zafari, Soghra Bornodeli, Zahra Soleimani, Shahram Ghasembaglou   +6 more
doaj   +1 more source

Editorial: Long noncoding RNAs in cancer [PDF]

Frontiers in Oncology
Silvia Jiménez-Morales, Khushbukhat Khan, Uttam Sharma   +2 more
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Epigenetics Approaches toward Precision Medicine for Idiopathic Pulmonary Fibrosis: Focus on DNA Methylation

Biomedicines, 2023
Genetic information is not transmitted solely by DNA but by the epigenetics process. Epigenetics describes molecular missing link pathways that could bridge the gap between the genetic background and environmental risk factors that contribute to the ...
Wiwin Is Effendi, Tatsuya Nagano
doaj   +1 more source

MALAT1: A Pivotal lncRNA in the Phenotypic Switch of Gastric Smooth Muscle Cells via the Targeting of the miR-449a/DLL1 Axis in Diabetic Gastroparesis

Frontiers in Pharmacology, 2021
Diabetic gastroparesis (DGP) is a common complication of diabetes mellitus (DM). Our previous study suggested that the expression of the long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is closely related to ...
Yanjuan Wang, Yan Wang, Boqian Zhu, Ying Zhu, Ya Jiang, Wenjie Xiong, Lin Lin, Yaoyao Gong   +7 more
doaj   +1 more source

Neuroprotective effects of long noncoding RNAs involved in ischemic postconditioning after ischemic stroke

Neural Regeneration Research, 2022
During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma, Chun-Yan Li, Si-Jia Zhang, Cheng-Hao Zang, Jin-Wei Yang, Zhen Wu, Guo-Dong Wang, Jie Liu, Wei Liu, Kuang-Pin Liu, Yu Liang, Xing-Kui Zhang, Jun-Jun Li, Jian-Hui Guo, Li-Yan Li   +14 more
doaj   +1 more source

Clinical Evaluation of LncRNA XIST and TUG1 Expression Levels in Patients with Hepatocellular Carcinoma [PDF]

Middle East Journal of Cancer
Background: Among long non-coding RNAs, as key regulators in oncogenesis, X-inactive specific transcript (XIST) and Taurine upregulated 1 (TUG1) are frequently reported in various cancers.
Sahar Ravanshad, Zohre Gerami, Salman Farsi, Mohammadhossein Taherynejad, Sobhan Jalali, Mohsen Aliakbarian, Hassan Mehrad-Majd   +6 more
doaj   +1 more source

Long Noncoding RNA Maternally Expressed Gene 3 Is Downregulated, and Its Insufficiency Correlates With Poor-Risk Stratification, Worse Treatment Response, as Well as Unfavorable Survival Data in Patients With Acute Myeloid Leukemia

Technology in Cancer Research & Treatment, 2020
Objective: Our study aimed to investigate the correlation of long noncoding RNA maternally expressed gene 3 expression with clinical features, treatment response, and survival profiles in patients with acute myeloid leukemia. Methods: Bone marrow samples
Chunling He MM, Xinmei Wang MM, Jing Luo MM, Yinghua Ma MM, Zhen Yang MM   +4 more
doaj   +1 more source