Results 31 to 40 of about 6,663,585 (252)

Knockdown of lncRNA OGFRP1 Inhibits Proliferation and Invasion of JEG-3 Cells Via AKT/mTOR Pathway

open access: yesTechnology in Cancer Research & Treatment, 2020
Increasing evidence indicates the pivotal role of long noncoding RNAs in a variety of cancers, but there is limited focus on the link between long noncoding RNAs and gestational choriocarcinoma.
Qian Meng BD, Haiyan Xue MD
doaj   +1 more source

The role of miRNA and lncRNA in heterotopic ossification pathogenesis

open access: yesStem Cell Research & Therapy, 2022
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures ...
Łukasz Pulik   +6 more
doaj   +1 more source

The Landscape of Regulatory Noncoding RNAs in Ewing’s Sarcoma

open access: yesBiomedicines, 2021
Ewing’s sarcoma (ES) is a pediatric sarcoma caused by a chromosomal translocation. Unlike in most cancers, the genomes of ES patients are very stable.
Connor Barrett   +3 more
doaj   +1 more source

Long Noncoding RNAs in Non-Small Cell Lung Cancer: State of the Art

open access: yes, 2020
Lung cancer is one of the most common malignancies worldwide. Despite a significant amount of basic and clinical research, mortality rates remain extremely high, especially for patients affected by advanced stage disease.
Arduino Aleksander Mangoni   +9 more
core   +1 more source

Long non-coding RNA-polycomb intimate rendezvous [PDF]

open access: yesOpen Biology, 2020
The interaction between polycomb-repressive complexes 1/2 (PRC1/2) and long non-coding RNA (lncRNA), such as the X inactive specific transcript Xist and the HOX transcript antisense RNA (HOTAIR), has been the subject of intense debate.
Andrea Cerase, Gian Gaetano Tartaglia
doaj   +1 more source

Long Noncoding RNA Plasmacytoma Variant Translocation 1 Is Increased in Multiple Myeloma and Correlates With Lower Induction Response

open access: yesTechnology in Cancer Research & Treatment, 2020
Objective: This study aimed to investigate the correlation of long noncoding RNA plasmacytoma variant translocation 1 with clinical features and prognosis in patients with multiple myeloma.
Pei Li MD   +3 more
doaj   +1 more source

Long Non-Coding RNAs in Insects

open access: yesAnimals, 2021
Only a small subset of all the transcribed RNAs are used as a template for protein translation, whereas RNA molecules that are not translated play a very important role as regulatory non-coding RNAs (ncRNAs).
Chhavi Choudhary   +9 more
doaj   +1 more source

MCALIGN: Stochastic Alignment of Noncoding DNA Sequences Based on an Evolutionary Model of Sequence Evolution [PDF]

open access: yes, 2004
A method is described for performing global alignment of noncoding DNA sequences based on an evolutionary model parameterized by the frequency distribution of lengths of insertion/deletion events (indels) and their rate relative to nucleotide ...
Johnson, Toby   +3 more
core   +1 more source

Landscape of tumor suppressor long noncoding RNAs in breast cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background The landscape and biological functions of tumor suppressor long noncoding RNAs in breast cancer are still unknown. Methods Data from whole transcriptome sequencing of 33 breast specimens in the Harbin Medical University Cancer Center cohort ...
Boran Pang   +6 more
doaj   +1 more source

Long non-coding RNAs in oncourology

open access: yesNon-coding RNA Research, 2021
For several decades, research in tumor biology has focused on the involvement of genes encoding a protein. Only recently has it been discovered that a whole class of molecules called non-coding RNAs (ncRNAs) play a key regulatory role in health and ...
Ilgiz Gareev   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy