Long Noncoding RNAs in Metabolic Syndrome Related Disorders [PDF]
Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (
Magdalena Losko +2 more
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Long noncoding RNAs in infection biology [PDF]
Long non-coding RNA have emerged as an increasingly well studied subset of non-coding RNAs (ncRNAs) following their recent discovery in a number of organisms including humans and characterization of their functional and regulatory roles in variety of ...
Vinod eScaria, Ayesha ePasha
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Long noncoding RNAs in hematopoiesis [version 1; referees: 2 approved]
Mammalian development is under tight control to ensure precise gene expression. Recent studies reveal a new layer of regulation of gene expression mediated by long noncoding RNAs.
Xu Zhang, Wenqian Hu
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Is Evolutionary Conservation a Useful Predictor for Cancer Long Noncoding RNAs? Insights from the Cancer LncRNA Census 3 [PDF]
Evolutionary conservation is a measure of gene functionality that is widely used to prioritise long noncoding RNAs (lncRNA) in cancer research. Intriguingly, while updating our Cancer LncRNA Census (CLC), we observed an inverse relationship between year ...
Adrienne Vancura +6 more
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KRAS-related noncoding RNAs in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a poor overall prognosis. However, curative resection during the early stages of the disease can greatly improve survival rates, highlighting the importance of early screening and detection.
Shuang-Ni Yu +6 more
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Panning for Long Noncoding RNAs
The recent advent of high-throughput approaches has revealed widespread transcription of the human genome, leading to a new appreciation of transcription regulation, especially from noncoding regions.
Li Yang, Xiao-Ou Zhang, Shanshan Zhu
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Post-transcriptional Regulation through Long Noncoding RNAs (lncRNAs) [PDF]
This book is a collection of eight articles, of which seven are reviews and one is a research paper, that together form a Special Issue that describes the roles that long noncoding RNAs (lncRNA) play in gene regulation at a post-transcriptional ...
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Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication - Table
Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication ...
Julie Tai-Schmiedel (8714484) +10 more
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Annotation of Full-Length Long Noncoding RNAs with Capture Long-Read Sequencing (CLS). [PDF]
Metazoan genomes produce thousands of long-noncoding RNAs (lncRNAs), of which just a small fraction have been well characterized. Understanding their biological functions requires accurate annotations, or maps of the precise location and structure of ...
Sílvia Carbonell Sala +10 more
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Assessing recent selection and functionality at long noncoding RNA loci in the mouse genome [PDF]
This work was supported by the Biotechnology and Biological Sciences Research Council and The Wellcome Trust. A.N. was supported by the Swiss National Science Foundation (Grant: PZ00P3_142636). H.K. was supported by the European Research Council Starting
Ness, Rob W +26 more
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