Results 1 to 10 of about 243,847 (257)

The Landscape of Regulatory Noncoding RNAs in Ewing’s Sarcoma

open access: yesBiomedicines, 2021
Ewing’s sarcoma (ES) is a pediatric sarcoma caused by a chromosomal translocation. Unlike in most cancers, the genomes of ES patients are very stable.
Connor Barrett   +3 more
doaj   +2 more sources

Noncoding RNAs in human intervertebral disc degeneration: An integrated microarray study

open access: yesGenomics Data, 2015
Accumulating evidence indicates that noncoding RNAs play important roles in a multitude of biological processes. The striking findings of miRNAs (microRNAs) and lncRNAs (long noncoding RNAs) as members of noncoding RNAs open up an exciting era in the ...
Xu Liu   +9 more
doaj   +2 more sources

Noncoding RNAs Emerging as Drugs or Drug Targets: Their Chemical Modification, Bio-Conjugation and Intracellular Regulation

open access: yesMolecules, 2022
With the increasing understanding of various disease-related noncoding RNAs, ncRNAs are emerging as novel drugs and drug targets. Nucleic acid drugs based on different types of noncoding RNAs have been designed and tested.
Jin Wang, Tian Tian, Xin Li, Yan Zhang
doaj   +1 more source

Neuroprotective effects of long noncoding RNAs involved in ischemic postconditioning after ischemic stroke

open access: yesNeural Regeneration Research, 2022
During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma   +14 more
doaj   +1 more source

Vaccine Formulation Strategies and Challenges Involved in RNA Delivery for Modulating Biomarkers of Cardiovascular Diseases: A Race from Laboratory to Market

open access: yesVaccines, 2023
It has been demonstrated that noncoding RNAs have significant physiological and pathological roles. Modulation of noncoding RNAs may offer therapeutic approaches as per recent findings. Small RNAs, mostly long noncoding RNAs, siRNA, and microRNAs make up
Md. Adil Shaharyar   +7 more
doaj   +1 more source

The emerging role of small non-coding RNA in renal cell carcinoma

open access: yesTranslational Oncology, 2021
Noncoding RNAs are transcribed in the most regions of the human genome, divided into small noncoding RNAs (less than 200 nt) and long noncoding RNAs (more than 200 nt) according to their size.
Lifeng Ding   +9 more
doaj   +1 more source

Integrated Profiling Revealed Potential Regulatory Networks Among Long Noncoding RNAs and mRNAs in Mucosal Gastric Cancer

open access: yesTechnology in Cancer Research & Treatment, 2020
Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient ...
Ke-kang Sun MD   +4 more
doaj   +1 more source

Interaction between N 6-methyladenosine (m6A) modification and noncoding RNAs in cancer

open access: yesMolecular Cancer, 2020
As a critical internal RNA modification in higher eukaryotes, N 6-methyladenosine (m6A) has become the hotspot of epigenetics research in recent years.
Yi Chen   +4 more
doaj   +1 more source

Context-Dependent Regulation of Gene Expression by Non-Canonical Small RNAs

open access: yesNon-Coding RNA, 2022
In recent functional genomics studies, a large number of non-coding RNAs have been identified. It has become increasingly apparent that noncoding RNAs are crucial players in a wide range of cellular and physiological functions.
Kinga Plawgo, Katarzyna Dorota Raczynska
doaj   +1 more source

The Landscape of Noncoding RNA in Pulmonary Hypertension

open access: yesBiomolecules, 2022
The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding RNA transcripts playing crucial roles.
Lin Deng   +4 more
doaj   +1 more source

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