Genetic plasma biomarkers associated with ischemic stroke
Aim: Stroke is one of the leading causes of death and disability worldwide. Plasma biomarkers have long been used to evaluate physiological or pathological processes and to make predictions about the outcome of stroke patients.
Mihai Andrei Ruscu+8 more
doaj +1 more source
Acknowledgement to Reviewers of Non-Coding RNA in 2018
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Non-Coding RNA Editorial Office
doaj +1 more source
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato+10 more
doaj +1 more source
Acknowledgement to Reviewers of Non-Coding RNA in 2016
The editors of Non‐Coding RNA would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...]
Non-Coding RNA Editorial Office
doaj +1 more source
Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B.+4 more
core +1 more source
limma powers differential expression analyses for RNA-sequencing and microarray studies
limma is an R/Bioconductor software package that provides an integrated solution for analysing data from gene expression experiments. It contains rich features for handling complex experimental designs and for information borrowing to overcome the ...
Matthew E. Ritchie+6 more
semanticscholar +1 more source
Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’ [PDF]
The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts.
Matthias Schaefer+2 more
doaj +1 more source
Evaluation of the LncRNA TMPO AS-1 Expression Level in Melanoma Tissues in Comparison to Paired Normal Marginal Tissues [PDF]
Background: Long noncoding RNA (lncRNA) is recognized as an essential controller of gene expression and other activities of the cells. Additionally, lncRNAs have a critical role in the progression and growth of human malignancies, like melanoma.
Habib Zarredar+6 more
doaj +1 more source
Cellular mRNAs access second ORFs using a novel amino acid sequence-dependent coupled translation termination-reinitiation mechanism [PDF]
Polycistronic transcripts are considered rare in the human genome. Initiation of translation of internal ORFs of eukaryotic genes has been shown to use either leaky scanning or highly structured IRES regions to access initiation codons.
Croft, Wayne D.+4 more
core +1 more source
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions.
Michael I. Love+2 more
semanticscholar +1 more source