Results 21 to 30 of about 2,455,342 (249)

Physiological tissue-specific and age-related reduction of mouse TDP-43 levels is regulated by epigenetic modifications

open access: yesDisease Models & Mechanisms, 2022
The cellular level of TDP-43 (also known as TARDBP) is tightly regulated; increases or decreases in TDP-43 have deleterious effects in cells. The predominant mechanism responsible for the regulation of the level of TDP-43 is an autoregulatory negative ...
Miriam Pacetti   +7 more
doaj   +1 more source

m6 RNA methylation: an emerging common target in the immune response to cancer and severe acute respiratory syndrome-coronavirus-2 infection

open access: yesExploration of Medicine, 2023
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato   +10 more
doaj   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2018

open access: yesNon-Coding RNA, 2019
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages

open access: yesBone & Joint Research, 2023
Aims: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA.
Haokun Mo   +7 more
doaj   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2016

open access: yesNon-Coding RNA, 2017
The editors of Non‐Coding RNA would like to express their sincere gratitude to the following  reviewers for assessing manuscripts in 2016.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Prevalence of HEV infection markers in Chinese blood donors: a meta-analysis

open access: yesZhongguo shuxue zazhi, 2023
Objective To analyze the serological markers and RNA prevalence of HEV infection in Chinese voluntary blood donors in different regions of China, so as to provide basis for the necessity of HEV screening and the formulation of screening strategies for ...
Yuena XIE   +4 more
doaj   +1 more source

Evaluation of the LncRNA TMPO AS-1 Expression Level in Melanoma Tissues in Comparison to Paired Normal Marginal Tissues [PDF]

open access: yesMiddle East Journal of Cancer, 2023
Background: Long noncoding RNA (lncRNA) is recognized as an essential controller of gene expression and other activities of the cells. Additionally, lncRNAs have a critical role in the progression and growth of human malignancies, like melanoma.
Habib Zarredar   +6 more
doaj   +1 more source

Automated immunohistochemical assessment ability to evaluate estrogen and progesterone receptor status compared with quantitative reverse transcription-polymerase chain reaction in breast carcinoma patients [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2021
Background This study aimed to investigate the capability of an automated immunohistochemical (IHC) evaluation of hormonal receptor status in breast cancer patients compared to a well-validated quantitative reverse transcription–polymerase chain reaction
Taesung Jeon, Aeree Kim, Chungyeul Kim
doaj   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2017

open access: yesNon-Coding RNA, 2018
Peer review is an essential part in the publication process, ensuring that Non-Coding RNA maintains high quality standards for its published papers.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone

open access: yesBone & Joint Research, 2022
Aims: Osteoarthritis (OA) is a common degenerative joint disease. The osteocyte transcriptome is highly relevant to osteocyte biology. This study aimed to explore the osteocyte transcriptome in subchondral bone affected by OA.
Jun Zhou   +7 more
doaj   +1 more source

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