Results 21 to 30 of about 2,998,848 (249)

Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update

open access: yesPharmaceutics, 2020
Over the last two decades, dendritic cell (DC) vaccination has been studied extensively as active immunotherapy in cancer treatment and has been proven safe in all clinical trials both with respect to short and long-term side effects. For antigen-loading
Jan Dörrie   +3 more
doaj   +1 more source

STAR: ultrafast universal RNA-seq aligner

open access: yesBioinform., 2013
MOTIVATION Accurate alignment of high-throughput RNA-seq data is a challenging and yet unsolved problem because of the non-contiguous transcript structure, relatively short read lengths and constantly increasing throughput of the sequencing technologies.
Alexander Dobin   +8 more
semanticscholar   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2017

open access: yesNon-Coding RNA, 2018
Peer review is an essential part in the publication process, ensuring that Non-Coding RNA maintains high quality standards for its published papers.[...]
Non-Coding RNA Editorial Office
doaj   +1 more source

Osteoblast function in patients with idiopathic osteonecrosis of the femoral head: implications for a possible novel therapy

open access: yesBone & Joint Research, 2021
Aims: To investigate whether idiopathic osteonecrosis of the femoral head (ONFH) is related to impaired osteoblast activities. Methods: We cultured osteoblasts isolated from trabecular bone explants taken from the femoral head and the intertrochanteric ...
Leila Maestro-Paramio   +3 more
doaj   +1 more source

Novel cyanine dye as competitive ligand for probing the drug–nucleic acid interactions

open access: yesБіофізичний вісник, 2020
Background: During the past decades, increasing attention has been given to elucidating the molecular details of interactions between the pharmacological agents and nucleic acids since the drug–DNA complexation may lead to impairment of DNA replication ...
O. Zhytniakivska   +7 more
doaj   +1 more source

GSVA: gene set variation analysis for microarray and RNA-Seq data

open access: yesBMC Bioinformatics, 2013
Gene set enrichment (GSE) analysis is a popular framework for condensing information from gene expression profiles into a pathway or signature summary.
Sonja Hänzelmann   +2 more
semanticscholar   +1 more source

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

open access: yesGenome Biology, 2014
New normal linear modeling strategies are presented for analyzing read counts from RNA-seq experiments. The voom method estimates the mean-variance relationship of the log-counts, generates a precision weight for each observation and enters these into ...
C. Law, Yunshun Chen, Wei Shi, G. Smyth
semanticscholar   +1 more source

Peripheral blood mononuclear cells hepatitis C virus RNA as a predictor for the response to daclatasvir-containing oral antiviral regimen in chronic hepatitis C patients from the Damietta Governorate

open access: yesAl-Azhar Assiut Medical Journal, 2019
Background Eradication of hepatitis C virus (HCV) infection is the goal of direct-acting antivirals with a high rate of sustained virological response (SVR).
Alaa E Hashim   +4 more
doaj   +1 more source

Essence of demands of standard ISO 22000:2005 in aspect of assurances of milk health safety Istota wymagań standardu ISO 22000:2005 w aspekcie zapewnienia bezpieczeństwa zdrowotnego mleka [PDF]

open access: yesJournal of Agribusiness and Rural Development, 2008
The article presents the essence of demands of ISO 22000 as a standard which allows of control milk health safety in a more effective way. The implementation of system HACCP in the dairy companies undoubtedly make for more safety health products, however
Justyna Górna
doaj  

RNA-Guided Human Genome Engineering via Cas9

open access: yesScience, 2013
Genome Editing Clustered regularly interspaced short palindromic repeats (CRISPR) function as part of an adaptive immune system in a range of prokaryotes: Invading phage and plasmid DNA is targeted for cleavage by complementary CRISPR RNAs (crRNAs) bound
P. Mali   +7 more
semanticscholar   +1 more source

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