Results 41 to 50 of about 2,998,848 (249)
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.
Nucleic Acids Research, 1997 We describe a program, tRNAscan-SE, which identifies 99-100% of transfer RNA genes in DNA sequence while giving less than one false positive per 15 gigabases.
T. Lowe, S. Eddy
semanticscholar +1 more source
Transcriptome-wide association study reveals candidate causal genes for lumbar spinal stenosis
Bone & Joint Research, 2023 Aims: Lumbar spinal stenosis (LSS) is a common skeletal system disease that has been partly attributed to genetic variation. However, the correlation between genetic variation and pathological changes in LSS is insufficient, and it is difficult to ...
Jiawen Xu +5 more
doaj +1 more source
Scientia Marina, 2009 Spawning populations of European sardines (Sardina pilchardus) and anchovies (Engraulis encrasicolus) have become re-established in the southern North Sea after a ~30-year absence and now co-occur with sprat (Sprattus sprattus).
Philipp Kanstinger, Myron A. Peck
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Tissue effect on RNA:DNA ratios of marine fish larvae
Scientia Marina, 2009 In some routine studies of larval condition based on RNA:DNA ratios, heads and/or guts are removed for further age and feeding analysis. Also, during capture larvae are often found with their eyes missing. In this work we analysed tissues effects (muscle,
M. Pilar Olivar +2 more
doaj +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Validation of Suitable Reference Genes for Gene Expression Studies on Yak Testis Development
Animals, 2020 Testis has an important function in male reproduction. Its development is regulated by a large number of genes. The real-time reserve transcriptase-quantitative polymerase chain reaction (RT-qPCR) is a useful tool to evaluate the gene expression levels ...
Xuelan Zhou +9 more
doaj +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
PROSES IMPLEMENTASI BIOINFORMATIKA PADA DIGITALISASI DATA GENETIKA MANUSIA
Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2023 Perkembangan ilmu biologi menjadi pesat khususnya genetika yang mengakibatkan lonjakan berbagai eksperimen data genetika manusia sebagai pembawa informasi genetik untuk analisis pewarisan sifat dan duplikasi, serta untuk kegiatan forensik.
Herman Herman +2 more
doaj +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source