Results 51 to 60 of about 466,490 (274)

RAID: a comprehensive resource for human RNA-associated (RNA–RNA/RNA–protein) interaction [PDF]

open access: yesRNA, 2014
Transcriptomic analyses have revealed an unexpected complexity in the eukaryote transcriptome, which includes not only protein-coding transcripts but also an expanding catalog of noncoding RNAs (ncRNAs). Diverse coding and noncoding RNAs (ncRNAs) perform functions through interaction with each other in various cellular processes.
Kongning Li   +23 more
openaire   +3 more sources

Co-occurrence of European sardine (Sardina pilchardus), anchovy (Engraulis encrasicolus) and sprat (Sprattus sprattus) larvae in southern North Sea habitats: Abundance, distribution and biochemical-based condition

open access: yesScientia Marina, 2009
Spawning populations of European sardines (Sardina pilchardus) and anchovies (Engraulis encrasicolus) have become re-established in the southern North Sea after a ~30-year absence and now co-occur with sprat (Sprattus sprattus).
Philipp Kanstinger, Myron A. Peck
doaj   +1 more source

Tissue effect on RNA:DNA ratios of marine fish larvae

open access: yesScientia Marina, 2009
In some routine studies of larval condition based on RNA:DNA ratios, heads and/or guts are removed for further age and feeding analysis. Also, during capture larvae are often found with their eyes missing. In this work we analysed tissues effects (muscle,
M. Pilar Olivar   +2 more
doaj   +1 more source

Comparative Analysis of RNA Families Reveals Distinct Repertoires for Each Domain of Life [PDF]

open access: yesPLoS Comput Biol. 2012 8(11):e1002752, 2012
The RNA world hypothesis, that RNA genomes and catalysts preceded DNA genomes and genetically-encoded protein catalysts, has been central to models for the early evolution of life on Earth. A key part of such models is continuity between the earliest stages in the evolution of life and the RNA repertoires of extant lineages.
arxiv   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Validation of Suitable Reference Genes for Gene Expression Studies on Yak Testis Development

open access: yesAnimals, 2020
Testis has an important function in male reproduction. Its development is regulated by a large number of genes. The real-time reserve transcriptase-quantitative polymerase chain reaction (RT-qPCR) is a useful tool to evaluate the gene expression levels ...
Xuelan Zhou   +9 more
doaj   +1 more source

PROSES IMPLEMENTASI BIOINFORMATIKA PADA DIGITALISASI DATA GENETIKA MANUSIA

open access: yesSimetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2023
Perkembangan ilmu biologi menjadi pesat khususnya genetika yang  mengakibatkan lonjakan berbagai eksperimen data genetika manusia sebagai pembawa informasi genetik untuk analisis pewarisan sifat dan duplikasi, serta untuk kegiatan forensik.
Herman Herman   +2 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Interpretable RNA Foundation Model from Unannotated Data for Highly Accurate RNA Structure and Function Predictions [PDF]

open access: yesarXiv, 2022
Non-coding RNA structure and function are essential to understanding various biological processes, such as cell signaling, gene expression, and post-transcriptional regulations. These are all among the core problems in the RNA field. With the rapid growth of sequencing technology, we have accumulated a massive amount of unannotated RNA sequences.
arxiv  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

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