CircCLTH promotes skeletal muscle development and regeneration
Buffalo holds an excellent potential for beef production, and circRNA plays an important role in regulating myogenesis. However, the regulatory mechanism of circRNAs during buffalo skeletal muscle development has not been fully explored.
Mengjie Chen+12 more
doaj +1 more source
The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA. [PDF]
In the early 'RNA world' stage of life, RNA stored genetic information and catalyzed chemical reactions. However, the RNA world eventually gave rise to the DNA-RNA-protein world, and this transition included the 'genetic takeover' of information storage ...
Chen, Irene A+4 more
core +4 more sources
Certain Adenylated Non-Coding RNAs, Including 5′ Leader Sequences of Primary MicroRNA Transcripts, Accumulate in Mouse Cells following Depletion of the RNA Helicase MTR4 [PDF]
RNA surveillance plays an important role in posttranscriptional regulation. Seminal work in this field has largely focused on yeast as a model system, whereas exploration of RNA surveillance in mammals is only recently begun.
Anderson, James T.+4 more
core +8 more sources
RNA-RNA and RNA-protein interactions in coronavirus replication and transcription [PDF]
Coronavirus (CoV) RNA synthesis includes the replication of the viral genome, and the transcription of sgRNAs by a discontinuous mechanism. Both processes are regulated by RNA sequences such as the 5' and 3' untranslated regions (UTRs), and the transcription regulating sequences (TRSs) of the leader (TRS-L) and those preceding each gene (TRS-Bs). These
Solá Gurpegui, Isabel+4 more
openaire +4 more sources
Investigation of HIV-1 Gag binding with RNAs and Lipids using Atomic Force Microscopy [PDF]
Atomic Force Microscopy was utilized to study the morphology of Gag, {\Psi}RNA, and their binding complexes with lipids in a solution environment with 0.1{\AA} vertical and 1nm lateral resolution. TARpolyA RNA was used as a RNA control.
Chen, Shaolong+6 more
core +3 more sources
RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and throughput1. However, this approach captures only a static snapshot at a point in
G. L. Manno+22 more
semanticscholar +1 more source
Packet Replication and Noise in Reliable End-to-end Molecular Communication
In modern communication systems, noise represents the source of errors that disturb useful information signals for communication. In biological systems, however, noise plays important roles for their functions.
Taro Furubayashi+4 more
doaj +1 more source
Aims: Pellino1 (Peli1) has been reported to regulate various inflammatory diseases. This study aims to explore the role of Peli1 in the occurrence and development of osteoarthritis (OA), so as to find new targets for the treatment of OA.
Haokun Mo+7 more
doaj +1 more source
Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro [PDF]
An extract from whole oocytes of Xenopus laevis was shown to transcribe somatic-type 5S RNA genes approximately 100-fold more efficiently than oocyte-type 5S RNA genes.
Eversole-Cire, Pamela+4 more
core +1 more source
RAID: a comprehensive resource for human RNA-associated (RNA–RNA/RNA–protein) interaction [PDF]
Transcriptomic analyses have revealed an unexpected complexity in the eukaryote transcriptome, which includes not only protein-coding transcripts but also an expanding catalog of noncoding RNAs (ncRNAs). Diverse coding and noncoding RNAs (ncRNAs) perform functions through interaction with each other in various cellular processes.
Kongning Li+23 more
openaire +3 more sources