Results 201 to 210 of about 1,873,837 (361)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

The RNA binding protein Arid5a is an activator of TNF signaling in rheumatoid arthritis. [PDF]

JCI Insight
Li Y, Dey I, Vyas SP, Synackova A, Li D, Lubberts E, Ascherman DP, Draber P, Gaffen SL.   +8 more
europepmc   +1 more source

An Investigation of the 16‐S RNA Binding Sites of Ribosomal Proteins S4, S8, S15 and S20 from Escherichia coli [PDF]

, 1975
Ernst Ungewickell, Roger A. Garrett, Chantal Ehresmann, Patrick Stiegler, Peter Fellner   +4 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis. [PDF]

J Clin Invest
Kim HY, Mizrahi O, Lee W, Rosenthal SB, Han C, Yee BA, Blue SM, Diaz J, Jonnalagadda JP, Street LA, Hokutan K, Jang H, Miciano C, Ma CT, Bobkov AA, Sergienko E, Jackson MR, Jovanovic M, Stefanovic B, Kisseleva T, Yeo GW, Brenner DA.   +21 more
europepmc   +1 more source

Biochemical Analysis of Putative RNA-Binding Proteins in Porphyromonas gingivalis

, 2018
Jacob Mirpanah
openalex   +1 more source

Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1 [PDF]

, 2010
Marianna Teplova, Jikui Song, Hai Yan Gaw, А. А. Теплов, Dinshaw J. Patel   +4 more
openalex   +1 more source

Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2 [PDF]

, 2020
Lisbeth-Carolina Aguilar, Biplab Paul, Taylor Reiter, Louis Gendron, Arvind Arul Nambi Rajan, Rachel Montpetit, Christian Trahan, Sebastian Pechmann, Marlene Oeffinger, Ben Montpetit   +9 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability. [PDF]

Int J Oncol
Peng S, Chen Y, Wu J, Huang X, Hong L, Xie Y, Lei Y, Wei X, Yang P, Zhang J, Yang Q, Liu G, Li A, Liu S, Li J, Dai W, Hu Y, Wang J, Xiong J, Wang J.   +19 more
europepmc   +1 more source