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RNA-binding proteins regulate immune-related alternative splicing in inherited salt-losing tubulopathies. [PDF]
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Nature Methods, 2021
KIN-CLIP allows determination of binding and dissociation kinetics of RNA-binding proteins in cells.
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KIN-CLIP allows determination of binding and dissociation kinetics of RNA-binding proteins in cells.
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Molecular Biology Reports, 1990
We have recently shown that although pre-mRNA splicing in plants shares some features in common with splicing in vertebrates, there are some crucial differences. In plants there is a requirement for a general enrichment for A+U within the intron and there is no requirement for a 3 ' polypyrimidine tract (Goodall and Filipowicz, 1989).
G, Goodall +3 more
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We have recently shown that although pre-mRNA splicing in plants shares some features in common with splicing in vertebrates, there are some crucial differences. In plants there is a requirement for a general enrichment for A+U within the intron and there is no requirement for a 3 ' polypyrimidine tract (Goodall and Filipowicz, 1989).
G, Goodall +3 more
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1991
Publisher Summary The control of gene expression involves several steps at which specific sequences in pre-mRNA transcripts, as well as those in small RNA molecules, are recognized by proteins. RNA-binding proteins can be expected to mediate interactions in a variety of cellular processes, including those occurring in the transcription complex, the ...
J D, Keene, C C, Query
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Publisher Summary The control of gene expression involves several steps at which specific sequences in pre-mRNA transcripts, as well as those in small RNA molecules, are recognized by proteins. RNA-binding proteins can be expected to mediate interactions in a variety of cellular processes, including those occurring in the transcription complex, the ...
J D, Keene, C C, Query
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Drosophila RNA Binding Proteins
2006RNA binding proteins are fundamental mediators of gene expression. The use of the model organism Drosophila has helped to elucidate both tissue-specific and ubiquitous functions of RNA binding proteins. These proteins mediate all aspects of the mRNA lifespan including splicing, nucleocytoplasmic transport, localization, stability, translation, and ...
Chiara, Gamberi +2 more
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RNA binding proteins and selenocysteine
BioFactors, 2001AbstractSelenocysteine is incorporated into protein by a complex co‐translational mechanism that involves both cis and trans acting factors. Among the trans‐acting factors are RNA binding proteins that interact with the selenoprotein 3′ UTRs at a sequence known as the selenocysteine insertion sequence (SECIS). These factors are generally referred to as
P R, Copeland, D M, Driscoll
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Purification of RNA-Binding Proteins
2014The majority of regulatory RNA sequences exert their function through interaction with proteins. Therefore, the identification of RNA-binding proteins is the key step in understanding the role of many RNA motifs. Here, we describe a straightforward method to identify RNA-binding proteins.
Birgit, Ritter, Marc R, Reboll
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RNA-binding proteins in RNA interference
Molecular Biology, 2006Short RNAs (21–27 nt) silence genes that contain homologous nucleotide sequences; this is known as RNA silencing. This review considers the generation of short RNAs from their precursors: double-stranded RNAs, capable of inducing RNA interference, and hairpin RNAs, whose processing yields microRNAs, as well as the properties of RNA-binding domains that
R. N. Kotelnikov +3 more
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Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein
Biochemical Society Transactions, 2008PTB (polypyrimidine-tract-binding protein) is a ubiquitous RNA-binding protein. It was originally identified as a protein with a role in splicing but it is now known to function in a large number of diverse cellular processes including polyadenylation, mRNA stability and translation initiation.
Kirsty, Sawicka +3 more
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