Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1 [PDF]
Marianna Teplova +4 more
openalex +1 more source
Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2 [PDF]
Lisbeth-Carolina Aguilar +9 more
openalex +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
RNA-binding proteins connect Exon usage to the chromatin. [PDF]
Robertson H, Do HTT, Helms V.
europepmc +1 more source
Biochemical Analysis of Putative RNA-Binding Proteins in Porphyromonas gingivalis
Jacob Mirpanah
openalex +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review). [PDF]
Liu S +8 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
RNA-Binding Proteins: Modulators of Canonical Wnt Signaling Pathway. [PDF]
Czap MS, Singh V, Spiegelman VS.
europepmc +1 more source

