Results 221 to 230 of about 1,151,716 (261)

RNA-binding protein kinetics

Nature Methods, 2021
KIN-CLIP allows determination of binding and dissociation kinetics of RNA-binding proteins in cells.
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Plant RNA-binding proteins

Molecular Biology Reports, 1990
We have recently shown that although pre-mRNA splicing in plants shares some features in common with splicing in vertebrates, there are some crucial differences. In plants there is a requirement for a general enrichment for A+U within the intron and there is no requirement for a 3 ' polypyrimidine tract (Goodall and Filipowicz, 1989).
Goodall G, Levy J, Mieszczak M, Filipowicz W   +3 more
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Nuclear RNA-binding Proteins

1991
Publisher Summary The control of gene expression involves several steps at which specific sequences in pre-mRNA transcripts, as well as those in small RNA molecules, are recognized by proteins. RNA-binding proteins can be expected to mediate interactions in a variety of cellular processes, including those occurring in the transcription complex, the ...
J D, Keene, C C, Query
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Drosophila RNA Binding Proteins

2006
RNA binding proteins are fundamental mediators of gene expression. The use of the model organism Drosophila has helped to elucidate both tissue-specific and ubiquitous functions of RNA binding proteins. These proteins mediate all aspects of the mRNA lifespan including splicing, nucleocytoplasmic transport, localization, stability, translation, and ...
Chiara, Gamberi, Oona, Johnstone, Paul, Lasko   +2 more
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Circular RNAs Binding to RNA-Binding Proteins

High-throughput RNA sequencing yields novel noncoding RNAs called circular RNAs (circRNAs). They are extensively distributed across the transcriptomes of humans and other metazoans. Research has demonstrated their critical functions in multiple cellular developmental processes and diseases, including cancer, cognitive disorders, and neurodegenerative ...
Mandakini, Singh, Kirthik, Roshan, Srinivasan, Muthuswamy, Ajay, Kumar, Santosh, Kumar   +4 more
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Purification of RNA-Binding Proteins

2014
The majority of regulatory RNA sequences exert their function through interaction with proteins. Therefore, the identification of RNA-binding proteins is the key step in understanding the role of many RNA motifs. Here, we describe a straightforward method to identify RNA-binding proteins.
Birgit, Ritter, Marc R, Reboll
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The RNA-binding proteins

2015
This chapter details how RNA-binding proteins package RNA, protect RNA, organize RNA, and prepare RNA for post-transcriptional processes. It describes different kinds of RNA-binding and auxiliary domains that enable RNA-binding proteins to bind RNA in a versatile way.
David Elliott, Michael Ladomery
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RNA-binding proteins in RNA interference

Molecular Biology, 2006
Short RNAs (21–27 nt) silence genes that contain homologous nucleotide sequences; this is known as RNA silencing. This review considers the generation of short RNAs from their precursors: double-stranded RNAs, capable of inducing RNA interference, and hairpin RNAs, whose processing yields microRNAs, as well as the properties of RNA-binding domains that
R. N. Kotelnikov, S. G. Shpiz, A. I. Kalmykova, V. A. Gvozdev   +3 more
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Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

Biochemical Society Transactions, 2008
PTB (polypyrimidine-tract-binding protein) is a ubiquitous RNA-binding protein. It was originally identified as a protein with a role in splicing but it is now known to function in a large number of diverse cellular processes including polyadenylation, mRNA stability and translation initiation.
Kirsty, Sawicka, Martin, Bushell, Keith A, Spriggs, Anne E, Willis   +3 more
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RNA-binding proteins of bovine rotavirus

Journal of Virology, 1986
Two major bovine rotavirus proteins have RNA-binding activity as shown by an RNA overlay-protein blot assay. Of the six proteins in purified virions, only one showed RNA-binding activity. This 92,000-molecular-weight (92K) protein was present in both single- and double-shelled particles.
J F, Boyle, K V, Holmes
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